Ordering events in a developing genetic code

Preexisting partial genetic codes can fuse to evolve towards the complete Standard Genetic Code (SGC). Such code fusion provides a path of ‘least selection’, readily generating precursor codes that resemble the SGC. Consequently, such least selections produce the SGC via minimal, thus rapid, change....

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Main Author: Michael Yarus
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2023.2299615
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author Michael Yarus
author_facet Michael Yarus
author_sort Michael Yarus
collection DOAJ
description Preexisting partial genetic codes can fuse to evolve towards the complete Standard Genetic Code (SGC). Such code fusion provides a path of ‘least selection’, readily generating precursor codes that resemble the SGC. Consequently, such least selections produce the SGC via minimal, thus rapid, change. Optimal code evolution therefore requires delayed wobble. Early wobble encoding slows code evolution, very specifically diminishing the most likely SGC precursors: near-complete, accurate codes which are the products of code fusions. In contrast: given delayed wobble, the SGC can emerge from a truncation selection/evolutionary radiation based on proficient fused coding.
format Article
id doaj-art-d2a9b150a4f342289ea6f952672c55f8
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issn 1547-6286
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publishDate 2024-12-01
publisher Taylor & Francis Group
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series RNA Biology
spelling doaj-art-d2a9b150a4f342289ea6f952672c55f82025-08-20T02:49:59ZengTaylor & Francis GroupRNA Biology1547-62861555-85842024-12-0121125626310.1080/15476286.2023.2299615Ordering events in a developing genetic codeMichael Yarus0Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, USAPreexisting partial genetic codes can fuse to evolve towards the complete Standard Genetic Code (SGC). Such code fusion provides a path of ‘least selection’, readily generating precursor codes that resemble the SGC. Consequently, such least selections produce the SGC via minimal, thus rapid, change. Optimal code evolution therefore requires delayed wobble. Early wobble encoding slows code evolution, very specifically diminishing the most likely SGC precursors: near-complete, accurate codes which are the products of code fusions. In contrast: given delayed wobble, the SGC can emerge from a truncation selection/evolutionary radiation based on proficient fused coding.https://www.tandfonline.com/doi/10.1080/15476286.2023.2299615Wobblecodonanticodonhorizontal gene transfercode fusionanthology
spellingShingle Michael Yarus
Ordering events in a developing genetic code
RNA Biology
Wobble
codon
anticodon
horizontal gene transfer
code fusion
anthology
title Ordering events in a developing genetic code
title_full Ordering events in a developing genetic code
title_fullStr Ordering events in a developing genetic code
title_full_unstemmed Ordering events in a developing genetic code
title_short Ordering events in a developing genetic code
title_sort ordering events in a developing genetic code
topic Wobble
codon
anticodon
horizontal gene transfer
code fusion
anthology
url https://www.tandfonline.com/doi/10.1080/15476286.2023.2299615
work_keys_str_mv AT michaelyarus orderingeventsinadevelopinggeneticcode