Results of various somatic mutations detection in patients with chronic myeloid leukemia

Results of various somatic mutations detection in patients with chronic myeloid leukemia

Background. Somatic mutations in chronic myeloid leukemia (CML) patients are considered as possible factors for the failure of tyrosine kinase inhibitor (TKI) therapy, and the study of their characteristics is of interest.Aim. To evaluate the genetic profile of blood cells in CML patients using next...

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Bibliographic Details
Main Authors: E. A. Kuzmina, E. Yu. Chelysheva, B. V. Biderman, O. A. Shukhov, E. A. Stepanova, E. P. Gadzhieva, A. N. Petrova, I. S. Nemchenko, A. V. Bykova, M. A. Guryanova, A. V. Kokhno, A. G. Turkina, A. B. Sudarikov
Format: Article
Language:Russian
Published: ABV-press 2024-12-01
Series:Онкогематология
Subjects:
chronic myeloid leukemia
somatic mutation
resistance
therapy failure
next-generation sequencing
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/983
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