Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone

Abstract Background Marine sponges and their microbiomes function together as holobionts, playing essential roles in ecosystem dynamics and exhibiting remarkable adaptability across depth gradients. This study utilized a multi-omics approach, integrating microbiome and metabolome analyses, to invest...

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Main Authors: Benoît Paix, Alexane Thivet, Celso Domingos, Özlem Erol, Niels van der Windt, Young H. Choi, Nicole J. de Voogd
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Microbiome
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Online Access:https://doi.org/10.1186/s40168-025-02146-2
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author Benoît Paix
Alexane Thivet
Celso Domingos
Özlem Erol
Niels van der Windt
Young H. Choi
Nicole J. de Voogd
author_facet Benoît Paix
Alexane Thivet
Celso Domingos
Özlem Erol
Niels van der Windt
Young H. Choi
Nicole J. de Voogd
author_sort Benoît Paix
collection DOAJ
description Abstract Background Marine sponges and their microbiomes function together as holobionts, playing essential roles in ecosystem dynamics and exhibiting remarkable adaptability across depth gradients. This study utilized a multi-omics approach, integrating microbiome and metabolome analyses, to investigate adaptive strategies in sponge holobionts inhabiting the mesophotic (80–125 m), upper-rariphotic (125–200 m), and lower-rariphotic (200–305 m) zones of Curaçao. We hypothesized that depth-related environmental factors drive distinct adaptive strategies, similar to patterns observed in fish and coral assemblages. Results Results revealed major differences in holometabolomes and microbial communities between Demospongiae and Hexactinellida sponges, reflecting class-specific adaptive strategies. Notably, phospholipid homeoviscous adaptation to temperature and pressure might emerge as a key mechanism in phosphorus metabolism. Adaptations in nitrogen metabolism were linked to diverse ammonia oxidizing archaea (AOA) symbionts, and dissolved organic matter cycling. Hexactinellid microbiomes exhibited intra-specific heterogeneity; however, species-specific associations with AOA symbionts such as Cenarchaeum and Nitrosopumilus were observed. Additionally, the lower-rariphotic hexactinellid holometabolomes highlighted the significance of the nested ecosystem concept through the identification of secondary metabolites produced by their associated fauna (aphrocallistins by zoanthids and xanthurenic acid by shrimp). Conclusions This study highlights the ecological significance of sponge holobionts in mesophotic and rariphotic ecosystems, revealing diverse adaptations to unique physicochemical conditions and biotic interactions. Video Abstract
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spelling doaj-art-d2a340e7f880401093fc0d3b30b686912025-08-20T03:45:34ZengBMCMicrobiome2049-26182025-07-0113112210.1186/s40168-025-02146-2Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zoneBenoît Paix0Alexane Thivet1Celso Domingos2Özlem Erol3Niels van der Windt4Young H. Choi5Nicole J. de Voogd6UMR CARRTEL, INRAE-Université Savoie Mont-BlancNaturalis Biodiversity CenterCIIMAR-Interdisciplinary Centre of Marine and Environmental Research, University of PortoInstitute of Biology (IBL), Leiden UniversityNaturalis Biodiversity CenterInstitute of Biology (IBL), Leiden UniversityNaturalis Biodiversity CenterAbstract Background Marine sponges and their microbiomes function together as holobionts, playing essential roles in ecosystem dynamics and exhibiting remarkable adaptability across depth gradients. This study utilized a multi-omics approach, integrating microbiome and metabolome analyses, to investigate adaptive strategies in sponge holobionts inhabiting the mesophotic (80–125 m), upper-rariphotic (125–200 m), and lower-rariphotic (200–305 m) zones of Curaçao. We hypothesized that depth-related environmental factors drive distinct adaptive strategies, similar to patterns observed in fish and coral assemblages. Results Results revealed major differences in holometabolomes and microbial communities between Demospongiae and Hexactinellida sponges, reflecting class-specific adaptive strategies. Notably, phospholipid homeoviscous adaptation to temperature and pressure might emerge as a key mechanism in phosphorus metabolism. Adaptations in nitrogen metabolism were linked to diverse ammonia oxidizing archaea (AOA) symbionts, and dissolved organic matter cycling. Hexactinellid microbiomes exhibited intra-specific heterogeneity; however, species-specific associations with AOA symbionts such as Cenarchaeum and Nitrosopumilus were observed. Additionally, the lower-rariphotic hexactinellid holometabolomes highlighted the significance of the nested ecosystem concept through the identification of secondary metabolites produced by their associated fauna (aphrocallistins by zoanthids and xanthurenic acid by shrimp). Conclusions This study highlights the ecological significance of sponge holobionts in mesophotic and rariphotic ecosystems, revealing diverse adaptations to unique physicochemical conditions and biotic interactions. Video Abstracthttps://doi.org/10.1186/s40168-025-02146-2Multi-omicsSpongesMicrobiomeMetabolomeDepthRariphotic
spellingShingle Benoît Paix
Alexane Thivet
Celso Domingos
Özlem Erol
Niels van der Windt
Young H. Choi
Nicole J. de Voogd
Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
Microbiome
Multi-omics
Sponges
Microbiome
Metabolome
Depth
Rariphotic
title Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
title_full Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
title_fullStr Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
title_full_unstemmed Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
title_short Adaptive strategies of Caribbean sponge holobionts beyond the mesophotic zone
title_sort adaptive strategies of caribbean sponge holobionts beyond the mesophotic zone
topic Multi-omics
Sponges
Microbiome
Metabolome
Depth
Rariphotic
url https://doi.org/10.1186/s40168-025-02146-2
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