The need for adaptability in detection, characterization, and attribution of biosecurity threats
Abstract Modern biotechnology necessitates robust biosecurity protocols to address the risk of engineered biological threats. Current efforts focus on screening DNA and rejecting the synthesis of dangerous elements but face technical and logistical barriers. Screening should integrate into a broader...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-55436-y |
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| _version_ | 1850133865890316288 |
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| author | William Mo Christopher A. Vaiana Chris J. Myers |
| author_facet | William Mo Christopher A. Vaiana Chris J. Myers |
| author_sort | William Mo |
| collection | DOAJ |
| description | Abstract Modern biotechnology necessitates robust biosecurity protocols to address the risk of engineered biological threats. Current efforts focus on screening DNA and rejecting the synthesis of dangerous elements but face technical and logistical barriers. Screening should integrate into a broader strategy that addresses threats at multiple stages of development and deployment. The success of this approach hinges upon reliable detection, characterization, and attribution of engineered DNA. Recent advances notably aid the potential to both develop threats and analyze them. However, further work is needed to translate developments into biosecurity applications. This work reviews cutting-edge methods for DNA analysis and recommends avenues to improve biosecurity in an adaptable manner. |
| format | Article |
| id | doaj-art-d2a1c1b4cc264cb896bf9a66395f09c3 |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-d2a1c1b4cc264cb896bf9a66395f09c32025-08-20T02:31:51ZengNature PortfolioNature Communications2041-17232024-12-011511910.1038/s41467-024-55436-yThe need for adaptability in detection, characterization, and attribution of biosecurity threatsWilliam Mo0Christopher A. Vaiana1Chris J. Myers2Draper Scholar, The Charles Stark Draper Laboratory, Inc.The Charles Stark Draper Laboratory, Inc.Department of Electrical, Computer, and Energy Engineering, University of Colorado BoulderAbstract Modern biotechnology necessitates robust biosecurity protocols to address the risk of engineered biological threats. Current efforts focus on screening DNA and rejecting the synthesis of dangerous elements but face technical and logistical barriers. Screening should integrate into a broader strategy that addresses threats at multiple stages of development and deployment. The success of this approach hinges upon reliable detection, characterization, and attribution of engineered DNA. Recent advances notably aid the potential to both develop threats and analyze them. However, further work is needed to translate developments into biosecurity applications. This work reviews cutting-edge methods for DNA analysis and recommends avenues to improve biosecurity in an adaptable manner.https://doi.org/10.1038/s41467-024-55436-y |
| spellingShingle | William Mo Christopher A. Vaiana Chris J. Myers The need for adaptability in detection, characterization, and attribution of biosecurity threats Nature Communications |
| title | The need for adaptability in detection, characterization, and attribution of biosecurity threats |
| title_full | The need for adaptability in detection, characterization, and attribution of biosecurity threats |
| title_fullStr | The need for adaptability in detection, characterization, and attribution of biosecurity threats |
| title_full_unstemmed | The need for adaptability in detection, characterization, and attribution of biosecurity threats |
| title_short | The need for adaptability in detection, characterization, and attribution of biosecurity threats |
| title_sort | need for adaptability in detection characterization and attribution of biosecurity threats |
| url | https://doi.org/10.1038/s41467-024-55436-y |
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