Synthesis and Antimicrobial Activity of Some Chalcone Derivatives
In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. The synthesized compounds wer...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2008/876257 |
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| _version_ | 1849473423957295104 |
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| author | Y. Rajendra Prasad A. Lakshmana Rao R. Rambabu |
| author_facet | Y. Rajendra Prasad A. Lakshmana Rao R. Rambabu |
| author_sort | Y. Rajendra Prasad |
| collection | DOAJ |
| description | In an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. The synthesized compounds were characterized by means of their IR, 1H-NMR spectral data and elemental analysis. All the compounds were tested for their antibacterial and antifungal activities by the cup plate method. |
| format | Article |
| id | doaj-art-d29cf35669d841ee99b54b77da516691 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-d29cf35669d841ee99b54b77da5166912025-08-20T03:24:08ZengWileyE-Journal of Chemistry0973-49452090-98102008-01-015346146610.1155/2008/876257Synthesis and Antimicrobial Activity of Some Chalcone DerivativesY. Rajendra Prasad0A. Lakshmana Rao1R. Rambabu2University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, IndiaUniversity College of Pharmaceutical Sciences, Andhra University, Visakhapatnam-530 003, Andhra Pradesh, IndiaIn an effort to develop antimicrobial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of aqueous solution of potassium hydroxide and ethanol at room temperature. The synthesized compounds were characterized by means of their IR, 1H-NMR spectral data and elemental analysis. All the compounds were tested for their antibacterial and antifungal activities by the cup plate method.http://dx.doi.org/10.1155/2008/876257 |
| spellingShingle | Y. Rajendra Prasad A. Lakshmana Rao R. Rambabu Synthesis and Antimicrobial Activity of Some Chalcone Derivatives E-Journal of Chemistry |
| title | Synthesis and Antimicrobial Activity of Some Chalcone Derivatives |
| title_full | Synthesis and Antimicrobial Activity of Some Chalcone Derivatives |
| title_fullStr | Synthesis and Antimicrobial Activity of Some Chalcone Derivatives |
| title_full_unstemmed | Synthesis and Antimicrobial Activity of Some Chalcone Derivatives |
| title_short | Synthesis and Antimicrobial Activity of Some Chalcone Derivatives |
| title_sort | synthesis and antimicrobial activity of some chalcone derivatives |
| url | http://dx.doi.org/10.1155/2008/876257 |
| work_keys_str_mv | AT yrajendraprasad synthesisandantimicrobialactivityofsomechalconederivatives AT alakshmanarao synthesisandantimicrobialactivityofsomechalconederivatives AT rrambabu synthesisandantimicrobialactivityofsomechalconederivatives |