PWRN1 low expression facilitates cancer progression and is an unfavorable prognosis factor in breast cancer

PWRN1 low expression facilitates cancer progression and is an unfavorable prognosis factor in breast cancer

Abstract Background Triple-negative breast cancer (TNBC) has a poor prognosis due to metastasis and recurrence. The LncRNA PWRN1 is lowly expressed in breast cancer, so we investigated the regulatory mechanism and prognostic value of PWRN1 in TNBC. Methods 135 TNBC patients were included. PWRN1 leve...

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Bibliographic Details
Main Authors: Hubao Yuan, Yuanwei Liu, Yong Jia, Xiaodong Yang, Dezhen Yang, Ming Dong, Xin Tang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
PWRN1
MiR-21-5p
Triple-negative breast cancer
Prognostic marker
Online Access:https://doi.org/10.1007/s12672-025-02538-8
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