Enteric fever in endemic areas of Indonesia: an increasing problem of resistance
Reported levels of antibiotic resistance in Salmonella Typhi from South Sulawesi, Indonesia were very low (< 1%) before 2001 and chloramphenicol remained the treatment of choice. Since 2001 however resistance has been rising and in 2007 6.8% of isolates were resistant to all three first line drug...
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| Format: | Article |
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The Journal of Infection in Developing Countries
2008-08-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/222 |
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| author | Mochammad Hatta Name Ratnawati |
| author_facet | Mochammad Hatta Name Ratnawati |
| author_sort | Mochammad Hatta |
| collection | DOAJ |
| description | Reported levels of antibiotic resistance in Salmonella Typhi from South Sulawesi, Indonesia were very low (< 1%) before 2001 and chloramphenicol remained the treatment of choice. Since 2001 however resistance has been rising and in 2007 6.8% of isolates were resistant to all three first line drugs: Ampicillin, chloramphenicol and co-trimoxazole. Ciprofloxacin resistance is currently at 3.90 %. At the same time there has been an increase in the number of reported cases. This may be because of improved diagnostics or it may be a genuine outbreak of drug resistant S. Typhi. In conclusion drug resistant typhoid fever will become a serious problem in Indonesia in the future, requiring the use of expensive drugs for the treatment of typhoid. A concerted effort is needed by the medical services to implement reliable diagnosis so that treatment or vaccination can be used to control the spread of drug resistant typhoid fever. |
| format | Article |
| id | doaj-art-d297699b57ef456f9e848a5c5e65432c |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2008-08-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d297699b57ef456f9e848a5c5e65432c2025-08-20T02:57:25ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802008-08-0120410.3855/jidc.222Enteric fever in endemic areas of Indonesia: an increasing problem of resistanceMochammad Hatta0Name Ratnawati1Department Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty Medicine, Hasanuddin University, MakassarDepartment Medical Microbiology, Molecular Biology and Immunology Laboratory, Faculty Medicine, Hasanuddin University, MakassarReported levels of antibiotic resistance in Salmonella Typhi from South Sulawesi, Indonesia were very low (< 1%) before 2001 and chloramphenicol remained the treatment of choice. Since 2001 however resistance has been rising and in 2007 6.8% of isolates were resistant to all three first line drugs: Ampicillin, chloramphenicol and co-trimoxazole. Ciprofloxacin resistance is currently at 3.90 %. At the same time there has been an increase in the number of reported cases. This may be because of improved diagnostics or it may be a genuine outbreak of drug resistant S. Typhi. In conclusion drug resistant typhoid fever will become a serious problem in Indonesia in the future, requiring the use of expensive drugs for the treatment of typhoid. A concerted effort is needed by the medical services to implement reliable diagnosis so that treatment or vaccination can be used to control the spread of drug resistant typhoid fever.https://jidc.org/index.php/journal/article/view/222keywords |
| spellingShingle | Mochammad Hatta Name Ratnawati Enteric fever in endemic areas of Indonesia: an increasing problem of resistance Journal of Infection in Developing Countries keywords |
| title | Enteric fever in endemic areas of Indonesia: an increasing problem of resistance |
| title_full | Enteric fever in endemic areas of Indonesia: an increasing problem of resistance |
| title_fullStr | Enteric fever in endemic areas of Indonesia: an increasing problem of resistance |
| title_full_unstemmed | Enteric fever in endemic areas of Indonesia: an increasing problem of resistance |
| title_short | Enteric fever in endemic areas of Indonesia: an increasing problem of resistance |
| title_sort | enteric fever in endemic areas of indonesia an increasing problem of resistance |
| topic | keywords |
| url | https://jidc.org/index.php/journal/article/view/222 |
| work_keys_str_mv | AT mochammadhatta entericfeverinendemicareasofindonesiaanincreasingproblemofresistance AT nameratnawati entericfeverinendemicareasofindonesiaanincreasingproblemofresistance |