Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner
The historical approach to assessing health risks of environmental chemicals has been to evaluate them one at a time. In fact, we are exposed every day to a wide variety of chemicals and are increasingly aware of potential health implications. Although considerable progress has been made in the scie...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2013/310904 |
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| author | Margaret M. MacDonell Lynne A. Haroun Linda K. Teuschler Glenn E. Rice Richard C. Hertzberg James P. Butler Young-Soo Chang Shanna L. Clark Alan P. Johns Camarie S. Perry Shannon S. Garcia John H. Jacobi Marcienne A. Scofield |
| author_facet | Margaret M. MacDonell Lynne A. Haroun Linda K. Teuschler Glenn E. Rice Richard C. Hertzberg James P. Butler Young-Soo Chang Shanna L. Clark Alan P. Johns Camarie S. Perry Shannon S. Garcia John H. Jacobi Marcienne A. Scofield |
| author_sort | Margaret M. MacDonell |
| collection | DOAJ |
| description | The historical approach to assessing health risks of environmental chemicals has been to evaluate them one at a time. In fact, we are exposed every day to a wide variety of chemicals and are increasingly aware of potential health implications. Although considerable progress has been made in the science underlying risk assessments for real-world exposures, implementation has lagged because many practitioners are unaware of methods and tools available to support these analyses. To address this issue, the US Environmental Protection Agency developed a toolbox of cumulative risk resources for contaminated sites, as part of a resource document that was published in 2007. This paper highlights information for nearly 80 resources from the toolbox and provides selected updates, with practical notes for cumulative risk applications. Resources are organized according to the main elements of the assessment process: (1) planning, scoping, and problem formulation; (2) environmental fate and transport; (3) exposure analysis extending to human factors; (4) toxicity analysis; and (5) risk and uncertainty characterization, including presentation of results. In addition to providing online access, plans for the toolbox include addressing nonchemical stressors and applications beyond contaminated sites and further strengthening resource accessibility to support evolving analyses for cumulative risk and sustainable communities. |
| format | Article |
| id | doaj-art-d28892e1c1e04f8995c830978ae172eb |
| institution | Kabale University |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-d28892e1c1e04f8995c830978ae172eb2025-02-03T01:01:14ZengWileyJournal of Toxicology1687-81911687-82052013-01-01201310.1155/2013/310904310904Cumulative Risk Assessment Toolbox: Methods and Approaches for the PractitionerMargaret M. MacDonell0Lynne A. Haroun1Linda K. Teuschler2Glenn E. Rice3Richard C. Hertzberg4James P. Butler5Young-Soo Chang6Shanna L. Clark7Alan P. Johns8Camarie S. Perry9Shannon S. Garcia10John H. Jacobi11Marcienne A. Scofield12Environmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USAENVIRON International Corporation, Emeryville, CA 94608, USAUS Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Cincinnati, OH 45268, USAUS Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, Cincinnati, OH 45268, USABiomathematics Consulting and Department of Environmental and Occupational Health, Emory University, Atlanta, GA 30322, USAEnvironmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USAEnvironmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USASynergy Toxicology, Boerne, TX 78006, USABaker Hughes, Tulsa, OK 74107, USAToxStrategies, Austin, TX 78759, USATEAM Integrated Engineering, Inc., San Antonio, TX 78216, USAEnvironmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USAEnvironmental Science Division, Argonne National Laboratory, Argonne, IL 60439, USAThe historical approach to assessing health risks of environmental chemicals has been to evaluate them one at a time. In fact, we are exposed every day to a wide variety of chemicals and are increasingly aware of potential health implications. Although considerable progress has been made in the science underlying risk assessments for real-world exposures, implementation has lagged because many practitioners are unaware of methods and tools available to support these analyses. To address this issue, the US Environmental Protection Agency developed a toolbox of cumulative risk resources for contaminated sites, as part of a resource document that was published in 2007. This paper highlights information for nearly 80 resources from the toolbox and provides selected updates, with practical notes for cumulative risk applications. Resources are organized according to the main elements of the assessment process: (1) planning, scoping, and problem formulation; (2) environmental fate and transport; (3) exposure analysis extending to human factors; (4) toxicity analysis; and (5) risk and uncertainty characterization, including presentation of results. In addition to providing online access, plans for the toolbox include addressing nonchemical stressors and applications beyond contaminated sites and further strengthening resource accessibility to support evolving analyses for cumulative risk and sustainable communities.http://dx.doi.org/10.1155/2013/310904 |
| spellingShingle | Margaret M. MacDonell Lynne A. Haroun Linda K. Teuschler Glenn E. Rice Richard C. Hertzberg James P. Butler Young-Soo Chang Shanna L. Clark Alan P. Johns Camarie S. Perry Shannon S. Garcia John H. Jacobi Marcienne A. Scofield Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner Journal of Toxicology |
| title | Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner |
| title_full | Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner |
| title_fullStr | Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner |
| title_full_unstemmed | Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner |
| title_short | Cumulative Risk Assessment Toolbox: Methods and Approaches for the Practitioner |
| title_sort | cumulative risk assessment toolbox methods and approaches for the practitioner |
| url | http://dx.doi.org/10.1155/2013/310904 |
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