Reye syndrome and liver transplantation

Reye syndrome is a rare, but severe and often fatal disease. The etiology of the classical Reye syndrome is unknown, but it is typically preceded by a viral infection with a free interval of three to five days. The main physiopathological hypothesis is a mitochondrial metabolism insult causin...

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Main Authors: Murat Cağ, Anne-Catherine Saouli, Maxime Audet, Philippe Wolf, Jacques Cinqualbre
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2010-12-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/5050
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author Murat Cağ
Anne-Catherine Saouli
Maxime Audet
Philippe Wolf
Jacques Cinqualbre
author_facet Murat Cağ
Anne-Catherine Saouli
Maxime Audet
Philippe Wolf
Jacques Cinqualbre
author_sort Murat Cağ
collection DOAJ
description Reye syndrome is a rare, but severe and often fatal disease. The etiology of the classical Reye syndrome is unknown, but it is typically preceded by a viral infection with a free interval of three to five days. The main physiopathological hypothesis is a mitochondrial metabolism insult causing acute liver failure and encephalopathy. Survivors present serious neurological sequelae. The treatment of Reye syndrome is usually medical with intensive care management. Herein, we present the clinical case of a six-month-old baby diagnosed with Reye syndrome with a fulminant hepatitis, who was successfully liver transplanted with an auxiliary partial orthotopic liver transplantation.
format Article
id doaj-art-d281c9cc9b0a4ef5b8eeccc775d5b706
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issn 0041-4301
2791-6421
language English
publishDate 2010-12-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-d281c9cc9b0a4ef5b8eeccc775d5b7062025-08-20T02:55:41ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212010-12-01526Reye syndrome and liver transplantationMurat Cağ0Anne-Catherine SaouliMaxime AudetPhilippe WolfJacques CinqualbreDepartment of Liver Diseases, Gastroenterologic Surgery and Multiorgan Transplantation, Multiorgan Transplantation Unit, Hautepierre Hospital, University of Strasbourg. Reye syndrome is a rare, but severe and often fatal disease. The etiology of the classical Reye syndrome is unknown, but it is typically preceded by a viral infection with a free interval of three to five days. The main physiopathological hypothesis is a mitochondrial metabolism insult causing acute liver failure and encephalopathy. Survivors present serious neurological sequelae. The treatment of Reye syndrome is usually medical with intensive care management. Herein, we present the clinical case of a six-month-old baby diagnosed with Reye syndrome with a fulminant hepatitis, who was successfully liver transplanted with an auxiliary partial orthotopic liver transplantation. https://turkjpediatr.org/article/view/5050
spellingShingle Murat Cağ
Anne-Catherine Saouli
Maxime Audet
Philippe Wolf
Jacques Cinqualbre
Reye syndrome and liver transplantation
The Turkish Journal of Pediatrics
title Reye syndrome and liver transplantation
title_full Reye syndrome and liver transplantation
title_fullStr Reye syndrome and liver transplantation
title_full_unstemmed Reye syndrome and liver transplantation
title_short Reye syndrome and liver transplantation
title_sort reye syndrome and liver transplantation
url https://turkjpediatr.org/article/view/5050
work_keys_str_mv AT muratcag reyesyndromeandlivertransplantation
AT annecatherinesaouli reyesyndromeandlivertransplantation
AT maximeaudet reyesyndromeandlivertransplantation
AT philippewolf reyesyndromeandlivertransplantation
AT jacquescinqualbre reyesyndromeandlivertransplantation