Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients

ABSTRACT Background With the rapid increase in China's aging population, cognitive impairment in the elderly has become a significant public health issue. Aims In this study we performed a cross‐sectional analysis to comprehensively investigate the relationship between cognitive function and em...

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Main Authors: Nan Wang, Qunying Zhang, Peng Li, Lilan Guo, Xiaoman Wu, Qiuyun Tu
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Brain and Behavior
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Online Access:https://doi.org/10.1002/brb3.70170
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author Nan Wang
Qunying Zhang
Peng Li
Lilan Guo
Xiaoman Wu
Qiuyun Tu
author_facet Nan Wang
Qunying Zhang
Peng Li
Lilan Guo
Xiaoman Wu
Qiuyun Tu
author_sort Nan Wang
collection DOAJ
description ABSTRACT Background With the rapid increase in China's aging population, cognitive impairment in the elderly has become a significant public health issue. Aims In this study we performed a cross‐sectional analysis to comprehensively investigate the relationship between cognitive function and emotion, sleep, frailty, nutrition, and clinical variables in hospitalized geriatric patients according to age group and sex. We determined the most important risk factors for cognitive impairment. Method A total of 1121 inpatients were recruited from the Department of Gerontology at the Fifth Affiliated Hospital of Sun Yat‐sen University, China, from August 2023 to April 2024. Cognitive assessment was performed using the Mini‐Mental State Examination scale and Montreal Cognitive Assessment. The sleep quality was evaluated based on the Pittsburgh Sleep Quality Index, and anxiety and depression were evaluated based on the Hamilton Anxiety Scale and Hamilton Depression Scale. Results Sex and age differences existed with respect to cognition, emotion, and sleep quality. After full adjustment, age, education level, working status, hemoglobin level, activities of daily living, Hamilton Depression Scale, and Pittsburgh Sleep Quality Index scores were significantly and independently associated with cognitive impairment. Discussion Geriatric patients with a better mood, sleep and nutrition status, higher education level, and more social engagement performance had superior cognitive function. Interventions, such as valuing education, improving sleep, relaxing emotions, preventing anemia, and adjusting lifestyle, may help prevent the development of cognitive deficits. Elderly and female patients required special attention. Conclusions Various factors were shown to contribute to maintenance of cognitive function.
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spelling doaj-art-d27f71eceb5b4b859f7ac8787e517e022025-08-20T01:52:54ZengWileyBrain and Behavior2162-32792024-11-011411n/an/a10.1002/brb3.70170Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized PatientsNan Wang0Qunying Zhang1Peng Li2Lilan Guo3Xiaoman Wu4Qiuyun Tu5Department of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaDepartment of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaDepartment of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaDepartment of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaDepartment of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaDepartment of Gerontology and Geriatrics Fifth Affiliated Hospital of Sun Yat‐sen University Zhuhai Guangdong ChinaABSTRACT Background With the rapid increase in China's aging population, cognitive impairment in the elderly has become a significant public health issue. Aims In this study we performed a cross‐sectional analysis to comprehensively investigate the relationship between cognitive function and emotion, sleep, frailty, nutrition, and clinical variables in hospitalized geriatric patients according to age group and sex. We determined the most important risk factors for cognitive impairment. Method A total of 1121 inpatients were recruited from the Department of Gerontology at the Fifth Affiliated Hospital of Sun Yat‐sen University, China, from August 2023 to April 2024. Cognitive assessment was performed using the Mini‐Mental State Examination scale and Montreal Cognitive Assessment. The sleep quality was evaluated based on the Pittsburgh Sleep Quality Index, and anxiety and depression were evaluated based on the Hamilton Anxiety Scale and Hamilton Depression Scale. Results Sex and age differences existed with respect to cognition, emotion, and sleep quality. After full adjustment, age, education level, working status, hemoglobin level, activities of daily living, Hamilton Depression Scale, and Pittsburgh Sleep Quality Index scores were significantly and independently associated with cognitive impairment. Discussion Geriatric patients with a better mood, sleep and nutrition status, higher education level, and more social engagement performance had superior cognitive function. Interventions, such as valuing education, improving sleep, relaxing emotions, preventing anemia, and adjusting lifestyle, may help prevent the development of cognitive deficits. Elderly and female patients required special attention. Conclusions Various factors were shown to contribute to maintenance of cognitive function.https://doi.org/10.1002/brb3.70170cognitive functionemotionfrailtynutritionsleep quality
spellingShingle Nan Wang
Qunying Zhang
Peng Li
Lilan Guo
Xiaoman Wu
Qiuyun Tu
Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
Brain and Behavior
cognitive function
emotion
frailty
nutrition
sleep quality
title Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
title_full Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
title_fullStr Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
title_full_unstemmed Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
title_short Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients
title_sort association between cognitive function and emotion sleep frailty and nutrition in hospitalized patients
topic cognitive function
emotion
frailty
nutrition
sleep quality
url https://doi.org/10.1002/brb3.70170
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