An approach to analyze spatiotemporal patterns of gene expression at single-cell resolution in Candida albicans-infected mouse tongues

ABSTRACT Microbial gene expression measurements derived from infected organs are invaluable to understand pathogenesis. However, current methods are limited to “bulk” analyses that neglect microbial cell heterogeneity and the lesion's spatial architecture. Here, we report the use of hybridizati...

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Bibliographic Details
Main Authors: Elena Lindemann-Perez, Diana L. Rodríguez, J. Christian Pérez
Format: Article
Language:English
Published: American Society for Microbiology 2024-09-01
Series:mSphere
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Online Access:https://journals.asm.org/doi/10.1128/msphere.00282-24
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