Identification of CβS and ODC antimony resistance markers in anthroponotic cutaneous leishmaniasis field isolates by gene expression profiling

Identification of CβS and ODC antimony resistance markers in anthroponotic cutaneous leishmaniasis field isolates by gene expression profiling

Antiparasitic resistance represents a serious global public health concern with tremendous economic and safety implications. This study intended to investigate the expression of the two major resistant markers: cystathionine β synthase (CβS) and ornithine decarboxylase (ODC) in antimony unresponsive...

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Main Authors: Farzaneh Zarrinkar, Iraj Sharifi, Razieh Tavakoli Oliaee, Ali Afgar, Elaheh Molaakbari, Mehdi Bamorovat, Zahra Babaei, Ebrahim Eskandari, Ehsan Salarkia, Marzieh Asadi
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Parasite Epidemiology and Control
Subjects:
Antimonial resistance
Leishmania tropica
Genetic markers
Cystathionine β synthase
Ornithine decarboxylase
Online Access:http://www.sciencedirect.com/science/article/pii/S2405673125000066
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