Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese

Sixteen long-ripened, high-quality Cabrales cheeses from independent producers underwent a comprehensive biochemical and microbiological characterisation. Significant variations in total microbial counts and specific microbial groups were observed among the cheeses. A metataxonomic analysis identifi...

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Main Authors: Javier Rodríguez, Paula Rosa Suárez, Souvik Das, Lucía Vázquez, Sonam Lama, Ana Belén Flórez, Jyoti Prakash Tamang, Baltasar Mayo
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Foods
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Online Access:https://www.mdpi.com/2304-8158/14/13/2366
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author Javier Rodríguez
Paula Rosa Suárez
Souvik Das
Lucía Vázquez
Sonam Lama
Ana Belén Flórez
Jyoti Prakash Tamang
Baltasar Mayo
author_facet Javier Rodríguez
Paula Rosa Suárez
Souvik Das
Lucía Vázquez
Sonam Lama
Ana Belén Flórez
Jyoti Prakash Tamang
Baltasar Mayo
author_sort Javier Rodríguez
collection DOAJ
description Sixteen long-ripened, high-quality Cabrales cheeses from independent producers underwent a comprehensive biochemical and microbiological characterisation. Significant variations in total microbial counts and specific microbial groups were observed among the cheeses. A metataxonomic analysis identified 249 prokaryotic amplicon sequence variants (ASVs) and 99 eukaryotic ASVs, respectively, which were classified into 52 prokaryotic and 43 eukaryotic species. The predominant species included bacteria of the genera <i>Tetragenococcus</i>, <i>Lactococcus</i> (of which <i>Lactococcus lactis</i> was used as a starter), and <i>Staphylococcus</i>, followed by <i>Brevibacterium</i> and <i>Corynebacterium</i> species. The starter mould <i>Penicillium roqueforti</i> was highly abundant in all cheeses; <i>Debaryomyces hansenii</i>, <i>Geotrichum candidum</i>, and <i>Kluyveromyces</i> spp. constituted the subdominant fungal populations. Glutamic acid (≈20 mg g<sup>−1</sup>) was the most abundant free amino acid in all samples, followed by lysine, leucine, and valine (≈10–13 mg g<sup>−1</sup>). Moderate-to-high amounts of the biogenic amines tyramine and ornithine were detected. A large variation between cheeses of the main organic acids (lactic, acetic, or butyric) was detected. Differences between samples were also observed for the majority volatile compounds, which included organic acids, alcohols, esters, and ketones. Positive and negative correlations between bacterial and fungal species were detected, as well as between microbial populations and key biochemical markers. Among the latter, <i>Tetragenococcus halophilus</i> correlated positively with ethyl caprylate and hexanoic acid, and <i>Loigolactobacillus rennini</i> correlated positively with γ-aminobutyric acid. Conversely, <i>Staphylococcus equorum</i> showed a strong negative correlation with ethyl caprylate and capric acid. These microbial and biochemical insights enabled us to propose a microbiota-based starter culture comprising prokaryotic and eukaryotic components to enhance Cabrales cheese quality.
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spelling doaj-art-d25a704911ec445fb2b41e3cc60a440f2025-08-20T03:17:07ZengMDPI AGFoods2304-81582025-07-011413236610.3390/foods14132366Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales CheeseJavier Rodríguez0Paula Rosa Suárez1Souvik Das2Lucía Vázquez3Sonam Lama4Ana Belén Flórez5Jyoti Prakash Tamang6Baltasar Mayo7Departamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), Francisco Pintado Fe, 26, 33011 Oviedo, SpainDepartamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), Francisco Pintado Fe, 26, 33011 Oviedo, SpainDepartment of Microbiology, School of Life Sciences, Sikkim University, Science Building, Dara Goan, Tadong, Gangtok 737102, IndiaDepartamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), Francisco Pintado Fe, 26, 33011 Oviedo, SpainDepartment of Microbiology, School of Life Sciences, Sikkim University, Science Building, Dara Goan, Tadong, Gangtok 737102, IndiaDepartamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), Francisco Pintado Fe, 26, 33011 Oviedo, SpainDepartment of Microbiology, School of Life Sciences, Sikkim University, Science Building, Dara Goan, Tadong, Gangtok 737102, IndiaDepartamento de Microbiología y Bioquímica, Instituto de Productos Lácteos de Asturias (IPLA), Consejo Superior de Investigaciones Científicas (CSIC), Francisco Pintado Fe, 26, 33011 Oviedo, SpainSixteen long-ripened, high-quality Cabrales cheeses from independent producers underwent a comprehensive biochemical and microbiological characterisation. Significant variations in total microbial counts and specific microbial groups were observed among the cheeses. A metataxonomic analysis identified 249 prokaryotic amplicon sequence variants (ASVs) and 99 eukaryotic ASVs, respectively, which were classified into 52 prokaryotic and 43 eukaryotic species. The predominant species included bacteria of the genera <i>Tetragenococcus</i>, <i>Lactococcus</i> (of which <i>Lactococcus lactis</i> was used as a starter), and <i>Staphylococcus</i>, followed by <i>Brevibacterium</i> and <i>Corynebacterium</i> species. The starter mould <i>Penicillium roqueforti</i> was highly abundant in all cheeses; <i>Debaryomyces hansenii</i>, <i>Geotrichum candidum</i>, and <i>Kluyveromyces</i> spp. constituted the subdominant fungal populations. Glutamic acid (≈20 mg g<sup>−1</sup>) was the most abundant free amino acid in all samples, followed by lysine, leucine, and valine (≈10–13 mg g<sup>−1</sup>). Moderate-to-high amounts of the biogenic amines tyramine and ornithine were detected. A large variation between cheeses of the main organic acids (lactic, acetic, or butyric) was detected. Differences between samples were also observed for the majority volatile compounds, which included organic acids, alcohols, esters, and ketones. Positive and negative correlations between bacterial and fungal species were detected, as well as between microbial populations and key biochemical markers. Among the latter, <i>Tetragenococcus halophilus</i> correlated positively with ethyl caprylate and hexanoic acid, and <i>Loigolactobacillus rennini</i> correlated positively with γ-aminobutyric acid. Conversely, <i>Staphylococcus equorum</i> showed a strong negative correlation with ethyl caprylate and capric acid. These microbial and biochemical insights enabled us to propose a microbiota-based starter culture comprising prokaryotic and eukaryotic components to enhance Cabrales cheese quality.https://www.mdpi.com/2304-8158/14/13/2366traditional cheesesCabrales cheesecheese microbiotacheese biochemistrystarterslactic acid bacteria
spellingShingle Javier Rodríguez
Paula Rosa Suárez
Souvik Das
Lucía Vázquez
Sonam Lama
Ana Belén Flórez
Jyoti Prakash Tamang
Baltasar Mayo
Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
Foods
traditional cheeses
Cabrales cheese
cheese microbiota
cheese biochemistry
starters
lactic acid bacteria
title Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
title_full Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
title_fullStr Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
title_full_unstemmed Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
title_short Microbial and Biochemical Analyses of High-Quality, Long-Ripened, Blue-Veined Cabrales Cheese
title_sort microbial and biochemical analyses of high quality long ripened blue veined cabrales cheese
topic traditional cheeses
Cabrales cheese
cheese microbiota
cheese biochemistry
starters
lactic acid bacteria
url https://www.mdpi.com/2304-8158/14/13/2366
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