Osmotic demyelination syndrome: A pediatric case report and a systematic literature review
Osmotic Demyelination Syndrome (ODS) is a life-threatening neurologic disorder including two distinct types of demyelination: Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). While it's clear that the fast correction of low sodium levels is a key precipitating factor, the...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325005187 |
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| author | Y. Mouhcine Z. Ezzoulali H. Ouazzani I. Chaouche A. AKAMMAR N. EL Bouardi B. Alami Y. Alaoui Lamrani M. Maaroufi M. Boubbou |
| author_facet | Y. Mouhcine Z. Ezzoulali H. Ouazzani I. Chaouche A. AKAMMAR N. EL Bouardi B. Alami Y. Alaoui Lamrani M. Maaroufi M. Boubbou |
| author_sort | Y. Mouhcine |
| collection | DOAJ |
| description | Osmotic Demyelination Syndrome (ODS) is a life-threatening neurologic disorder including two distinct types of demyelination: Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). While it's clear that the fast correction of low sodium levels is a key precipitating factor, the underlying pathophysiological mechanisms that cause ODS are still being explored. The present paper describes a case of an eleven-year-old male patient diagnosed with ODS based on typical imaging findings. This case report sounds like it could be significant by providing a thorough overview of the pathological findings, clinical outcomes, and imaging findings associated with this condition, particularly in pediatric cases. It also demonstrates the crucial role of MRI in diagnosing this condition. |
| format | Article |
| id | doaj-art-d256cee876904678bfe8d4977bdbb0a4 |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-d256cee876904678bfe8d4977bdbb0a42025-08-20T02:36:42ZengElsevierRadiology Case Reports1930-04332025-09-012094449445510.1016/j.radcr.2025.05.084Osmotic demyelination syndrome: A pediatric case report and a systematic literature reviewY. Mouhcine0Z. Ezzoulali1H. Ouazzani2I. Chaouche3A. AKAMMAR4N. EL Bouardi5B. Alami6Y. Alaoui Lamrani7M. Maaroufi8M. Boubbou9Department of Mother and Child Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, Morocco; Corresponding Author.Department of Mother and Child Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, MoroccoDepartment of Mother and Child Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, MoroccoDepartment of Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, MoroccoDepartment of Mother and Child Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, MoroccoDepartment of Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, MoroccoDepartment of Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, MoroccoDepartment of Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, MoroccoDepartment of Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, MoroccoDepartment of Mother and Child Radiology–Chu Hassan II, Sidi Mohammed Ben Abdellah University-Fez, Fez, MoroccoOsmotic Demyelination Syndrome (ODS) is a life-threatening neurologic disorder including two distinct types of demyelination: Central Pontine Myelinolysis (CPM) and Extrapontine Myelinolysis (EPM). While it's clear that the fast correction of low sodium levels is a key precipitating factor, the underlying pathophysiological mechanisms that cause ODS are still being explored. The present paper describes a case of an eleven-year-old male patient diagnosed with ODS based on typical imaging findings. This case report sounds like it could be significant by providing a thorough overview of the pathological findings, clinical outcomes, and imaging findings associated with this condition, particularly in pediatric cases. It also demonstrates the crucial role of MRI in diagnosing this condition.http://www.sciencedirect.com/science/article/pii/S1930043325005187Osmotic demyelination syndromeExtrapontine myelinolysisCentral pontine myelinolysisSeizureHyponatremiaMRI |
| spellingShingle | Y. Mouhcine Z. Ezzoulali H. Ouazzani I. Chaouche A. AKAMMAR N. EL Bouardi B. Alami Y. Alaoui Lamrani M. Maaroufi M. Boubbou Osmotic demyelination syndrome: A pediatric case report and a systematic literature review Radiology Case Reports Osmotic demyelination syndrome Extrapontine myelinolysis Central pontine myelinolysis Seizure Hyponatremia MRI |
| title | Osmotic demyelination syndrome: A pediatric case report and a systematic literature review |
| title_full | Osmotic demyelination syndrome: A pediatric case report and a systematic literature review |
| title_fullStr | Osmotic demyelination syndrome: A pediatric case report and a systematic literature review |
| title_full_unstemmed | Osmotic demyelination syndrome: A pediatric case report and a systematic literature review |
| title_short | Osmotic demyelination syndrome: A pediatric case report and a systematic literature review |
| title_sort | osmotic demyelination syndrome a pediatric case report and a systematic literature review |
| topic | Osmotic demyelination syndrome Extrapontine myelinolysis Central pontine myelinolysis Seizure Hyponatremia MRI |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325005187 |
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