Serological assessment of PRO-C16 (type XVI collagen formation) reflects intestinal fibrostenotic strictures in patients with crohn’s disease

Serological assessment of PRO-C16 (type XVI collagen formation) reflects intestinal fibrostenotic strictures in patients with crohn’s disease

Abstract Background Fibrostenotic stricturing disease affects 30–50% of patients with Crohn’s disease (CD), leading to intestinal resection. Currently, there exists a great medical need to identify biomarkers related to fibrostenotic strictures for optimized patient management. Thus, we investigated...

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Bibliographic Details
Main Authors: Joachim H. Mortensen, M. Lindholm, L. Langholm, P. Giuffrida, D. Ruane, T. Manon-Jensen, G. Mazza, F. Caprioli, L. Pastorelli, A-C. Bay-Jensen, M. Pinzani, M. A. Karsdal, A. Di Sabatino
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Gastroenterology
Subjects:
Crohn's disease
Stenosis
Intestinal fibrosis
Biomarkers
Collagen
Type XVI collagen
Online Access:https://doi.org/10.1186/s12876-025-04146-w
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