What should you know about limbic encephalitis?
Autoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition....
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações
2012-10-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012&lng=en&tlng=en |
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| author | Sara Machado Amélia Nogueira Pinto Sarosh R. Irani |
| author_facet | Sara Machado Amélia Nogueira Pinto Sarosh R. Irani |
| author_sort | Sara Machado |
| collection | DOAJ |
| description | Autoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition. It used to be regarded as a rare disease, usually paraneoplastic and with poor prognosis. However, with the recent recognition of membrane-surface directed antibodies, it is now known that in a substantial proportion of cases there is no association with any malignancy and there is a good prognosis if treated. Hence, early recognition and prompt initiation of immunotherapies are of great importance. |
| format | Article |
| id | doaj-art-d2509d2c44c64f0da015ed064da1b792 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2012-10-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-d2509d2c44c64f0da015ed064da1b7922025-08-20T02:19:43ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272012-10-01701081782210.1590/S0004-282X2012001000012S0004-282X2012001000012What should you know about limbic encephalitis?Sara MachadoAmélia Nogueira PintoSarosh R. Irani0University of OxfordAutoimmune encephalitis is an inflammatory disorder characterized by a subacute impairment of short-term memory, psychiatric features and seizures. It is often associated with a variety of other neurological symptoms, and its differential diagnosis is wide, leading to challenges in its recognition. It used to be regarded as a rare disease, usually paraneoplastic and with poor prognosis. However, with the recent recognition of membrane-surface directed antibodies, it is now known that in a substantial proportion of cases there is no association with any malignancy and there is a good prognosis if treated. Hence, early recognition and prompt initiation of immunotherapies are of great importance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012&lng=en&tlng=enencefalite límbica autoimuneencefalopatiaantigénios intracelularesantigénios da superfície de membranacomplexo VGKCLGI1CASPRN-metilaspartatosíndrome paraneoplásicaimunoterapia |
| spellingShingle | Sara Machado Amélia Nogueira Pinto Sarosh R. Irani What should you know about limbic encephalitis? Arquivos de Neuro-Psiquiatria encefalite límbica autoimune encefalopatia antigénios intracelulares antigénios da superfície de membrana complexo VGKC LGI1 CASPR N-metilaspartato síndrome paraneoplásica imunoterapia |
| title | What should you know about limbic encephalitis? |
| title_full | What should you know about limbic encephalitis? |
| title_fullStr | What should you know about limbic encephalitis? |
| title_full_unstemmed | What should you know about limbic encephalitis? |
| title_short | What should you know about limbic encephalitis? |
| title_sort | what should you know about limbic encephalitis |
| topic | encefalite límbica autoimune encefalopatia antigénios intracelulares antigénios da superfície de membrana complexo VGKC LGI1 CASPR N-metilaspartato síndrome paraneoplásica imunoterapia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2012001000012&lng=en&tlng=en |
| work_keys_str_mv | AT saramachado whatshouldyouknowaboutlimbicencephalitis AT amelianogueirapinto whatshouldyouknowaboutlimbicencephalitis AT saroshrirani whatshouldyouknowaboutlimbicencephalitis |