USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation

USP25 attenuates anti-GBM nephritis in mice by negative feedback regulation of Th17 cell differentiation

Purpose This study aimed to elucidate the role of USP25 in a mouse model of anti-glomerular basement membrane glomerulonephritis (anti-GBM GN).Methods USP25-deficient anti-GBM GN mice were generated, and their nephritis progression was monitored. Naïve CD4+ T cells were isolated from spleen lymphocy...

Full description

Saved in:
Bibliographic Details
Main Authors: Ranran Xu, Fei Huang, Qingquan Liu, Yongman Lv, Liu Hu, Qian Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
USP25
anti-GBM GN
Th17 cells
RORγt
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2338932
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items