Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review

Antimicrobial use in animal husbandry is a common practice in developing countries as a response to the growing demand for animal-based foods. Veterinary antibiotics account for most of the antibiotics used worldwide. This review aims to provide an overview of the impact of antibiotic usage in lives...

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Main Authors: Tesfaye Admassu Abate, Alemayehu Godana Birhanu
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Environmental Health Insights
Online Access:https://doi.org/10.1177/11786302251357775
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author Tesfaye Admassu Abate
Alemayehu Godana Birhanu
author_facet Tesfaye Admassu Abate
Alemayehu Godana Birhanu
author_sort Tesfaye Admassu Abate
collection DOAJ
description Antimicrobial use in animal husbandry is a common practice in developing countries as a response to the growing demand for animal-based foods. Veterinary antibiotics account for most of the antibiotics used worldwide. This review aims to provide an overview of the impact of antibiotic usage in livestock production on the environment and its consequences in the emergence and spread of antibiotic resistance. The global estimate of antibiotic consumption in animals ranges from 63 000 to 106 000 tons annually. The most commonly used antibiotic classes include tetracyclines, sulfonamides, β-lactams, macrolides, and trimethoprim. Most of the antibiotics used in animal treatments are not fully metabolized within the animal’s body; instead, they are excreted and can enter the environment. This review also provides a brief overview of the fate of antibiotic residues and their behavior in the environment. In developing countries, in addition to the lack of data on antibiotic use trends, there are limitations in implementing scientific and regulatory frameworks for antibiotic use in livestock. To reduce the projected loss of lives associated with antimicrobial resistant infections, it is recommended to lower antibiotic contamination in the environment by implementing affordable and critical actions related to antibiotic usage and residual waste management. Actions such as rational use of antibiotics in all circumstances, reducing environmental exposure to antibiotics, research, and environmental surveillance are important to tackle the problems of antibiotic resistance, especially in low-income countries.
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spelling doaj-art-d23dc7488a9042ce8a967ffc94c69e772025-08-20T02:44:59ZengSAGE PublishingEnvironmental Health Insights1178-63022025-07-011910.1177/11786302251357775Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative ReviewTesfaye Admassu Abate0Alemayehu Godana Birhanu1Biotechnology Research Center, Institute of Advanced Science and Technology, Addis Ababa University, Addis Ababa, EthiopiaBiotechnology Research Center, Institute of Advanced Science and Technology, Addis Ababa University, Addis Ababa, EthiopiaAntimicrobial use in animal husbandry is a common practice in developing countries as a response to the growing demand for animal-based foods. Veterinary antibiotics account for most of the antibiotics used worldwide. This review aims to provide an overview of the impact of antibiotic usage in livestock production on the environment and its consequences in the emergence and spread of antibiotic resistance. The global estimate of antibiotic consumption in animals ranges from 63 000 to 106 000 tons annually. The most commonly used antibiotic classes include tetracyclines, sulfonamides, β-lactams, macrolides, and trimethoprim. Most of the antibiotics used in animal treatments are not fully metabolized within the animal’s body; instead, they are excreted and can enter the environment. This review also provides a brief overview of the fate of antibiotic residues and their behavior in the environment. In developing countries, in addition to the lack of data on antibiotic use trends, there are limitations in implementing scientific and regulatory frameworks for antibiotic use in livestock. To reduce the projected loss of lives associated with antimicrobial resistant infections, it is recommended to lower antibiotic contamination in the environment by implementing affordable and critical actions related to antibiotic usage and residual waste management. Actions such as rational use of antibiotics in all circumstances, reducing environmental exposure to antibiotics, research, and environmental surveillance are important to tackle the problems of antibiotic resistance, especially in low-income countries.https://doi.org/10.1177/11786302251357775
spellingShingle Tesfaye Admassu Abate
Alemayehu Godana Birhanu
Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
Environmental Health Insights
title Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
title_full Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
title_fullStr Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
title_full_unstemmed Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
title_short Antibiotic Use in Livestock and Environmental Antibiotic Resistance: A Narrative Review
title_sort antibiotic use in livestock and environmental antibiotic resistance a narrative review
url https://doi.org/10.1177/11786302251357775
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