Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention
Thiazolidinediones (TZDs) are one of the major classes of antidiabetic drugs that are used widely. TZDs improve insulin resistance by activating peroxisome proliferator-activated receptor gamma (PPARγ) and ameliorate diabetic and other nephropathies, at least, in experimental animals. However, TZDs...
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Main Authors: | Shoko Horita, Motonobu Nakamura, Nobuhiko Satoh, Masashi Suzuki, George Seki |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2015/646423 |
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