Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity
Introduction. The aim of this study was to determine the prevalence of thyroid dysfunction in Greek patients with type 1 (T1DM) and type 2 (T2DM) diabetes mellitus as well as its possible relations to glycaemic control and to diabetic complications. Methods. A total of 1015 patients, consecutively f...
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| Language: | English |
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2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/6505814 |
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| author | Maria E. Barmpari Maria Kokkorou Anastasia Micheli Irene Alexiou Elefteria Spanou Marina Noutsou Anastasia Thanopoulou |
| author_facet | Maria E. Barmpari Maria Kokkorou Anastasia Micheli Irene Alexiou Elefteria Spanou Marina Noutsou Anastasia Thanopoulou |
| author_sort | Maria E. Barmpari |
| collection | DOAJ |
| description | Introduction. The aim of this study was to determine the prevalence of thyroid dysfunction in Greek patients with type 1 (T1DM) and type 2 (T2DM) diabetes mellitus as well as its possible relations to glycaemic control and to diabetic complications. Methods. A total of 1015 patients, consecutively followed in the Outpatient Diabetes Center, were studied. Anthropometric and biochemical measurements, occurrence of diabetes complications, and classical comorbidities were assessed. Average HbA1c of the previous year was calculated. Wellbeing was determined, using a 10-point optimal scale. All the above parameters were compared between subjects with or without thyroid disease. Results. All patients were euthyroid at the time of the study, either on thyroid medications or not. Hypothyroidism occurrence did not differ between T2DM and T1DM patients (37.1% versus 43.5%, p>0.05). Nodular goiter was observed more frequently in T2DM patients (34.1% versus 18.8%, p<0.05). T2DM patients with hypothyroidism compared to those without hypothyroidism had higher HbA1c (7.27% versus 6.98%, p<0.01), TChol (184.97 mg/dl versus 168.17 mg/dl, p<0.001), and higher HDL-Chol (51.28 mg/dl versus 46.77 mg/dl, p<0.01). T2DM patients without hypothyroidism had a better wellness feeling (7.5 versus 5.3 points, p<0.01). Conclusions. Screening for thyroid disease among T2DM patients should be routinely considered, as it is found to be an additional commorbidity. If it remains undiagnosed, it could aggravate the clinical course of the disease. |
| format | Article |
| id | doaj-art-d237da396cf64f1f95db27976877405a |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-d237da396cf64f1f95db27976877405a2025-08-20T03:24:07ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/65058146505814Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded ComorbidityMaria E. Barmpari0Maria Kokkorou1Anastasia Micheli2Irene Alexiou3Elefteria Spanou4Marina Noutsou5Anastasia Thanopoulou6Diabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceDiabetes Center, 2nd Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital of Athens, Athens, GreeceIntroduction. The aim of this study was to determine the prevalence of thyroid dysfunction in Greek patients with type 1 (T1DM) and type 2 (T2DM) diabetes mellitus as well as its possible relations to glycaemic control and to diabetic complications. Methods. A total of 1015 patients, consecutively followed in the Outpatient Diabetes Center, were studied. Anthropometric and biochemical measurements, occurrence of diabetes complications, and classical comorbidities were assessed. Average HbA1c of the previous year was calculated. Wellbeing was determined, using a 10-point optimal scale. All the above parameters were compared between subjects with or without thyroid disease. Results. All patients were euthyroid at the time of the study, either on thyroid medications or not. Hypothyroidism occurrence did not differ between T2DM and T1DM patients (37.1% versus 43.5%, p>0.05). Nodular goiter was observed more frequently in T2DM patients (34.1% versus 18.8%, p<0.05). T2DM patients with hypothyroidism compared to those without hypothyroidism had higher HbA1c (7.27% versus 6.98%, p<0.01), TChol (184.97 mg/dl versus 168.17 mg/dl, p<0.001), and higher HDL-Chol (51.28 mg/dl versus 46.77 mg/dl, p<0.01). T2DM patients without hypothyroidism had a better wellness feeling (7.5 versus 5.3 points, p<0.01). Conclusions. Screening for thyroid disease among T2DM patients should be routinely considered, as it is found to be an additional commorbidity. If it remains undiagnosed, it could aggravate the clinical course of the disease.http://dx.doi.org/10.1155/2017/6505814 |
| spellingShingle | Maria E. Barmpari Maria Kokkorou Anastasia Micheli Irene Alexiou Elefteria Spanou Marina Noutsou Anastasia Thanopoulou Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity Journal of Diabetes Research |
| title | Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity |
| title_full | Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity |
| title_fullStr | Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity |
| title_full_unstemmed | Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity |
| title_short | Thyroid Dysfunction among Greek Patients with Type 1 and Type 2 Diabetes Mellitus as a Disregarded Comorbidity |
| title_sort | thyroid dysfunction among greek patients with type 1 and type 2 diabetes mellitus as a disregarded comorbidity |
| url | http://dx.doi.org/10.1155/2017/6505814 |
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