Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement

Abstract Onion white rot, caused by Stromatinia cepivora, is a major soil-borne fungal disease that severely affects onion production. This study introduces a novel endophytic bacterium, Achromobacter xylosoxidans AX77 16S, isolated from healthy onion seeds, as a potential biocontrol agent and growt...

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Main Authors: Aya I. ELKasaby, Khalid M. Ghoneem, Yasser M. Shabana
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-10036-8
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author Aya I. ELKasaby
Khalid M. Ghoneem
Yasser M. Shabana
author_facet Aya I. ELKasaby
Khalid M. Ghoneem
Yasser M. Shabana
author_sort Aya I. ELKasaby
collection DOAJ
description Abstract Onion white rot, caused by Stromatinia cepivora, is a major soil-borne fungal disease that severely affects onion production. This study introduces a novel endophytic bacterium, Achromobacter xylosoxidans AX77 16S, isolated from healthy onion seeds, as a potential biocontrol agent and growth promoter. Out of 78 bacterial isolates screened, AX77 16S showed the strongest antifungal activity, inhibiting pathogen growth by 50% in dual culture assays. Its application significantly enhanced seed germination (up to 82%) and improved shoot and root development, increasing vigor indices by over 100% compared to untreated controls. The strain was identified by biochemical and molecular techniques and registered in GenBank (ON679518). GC–MS analysis revealed ten bioactive compounds in the bacterial filtrate, while scanning electron microscopy confirmed its damaging effects on fungal structures. Additionally, AX77 16S was formulated into a granular product that remained viable for up to one year. This study presents a promising, sustainable, and cost-effective alternative to chemical fungicides for managing onion white rot and promoting crop growth.
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spelling doaj-art-d225a0e0d4af4e1b9623c1371fd927992025-08-20T03:42:29ZengNature PortfolioScientific Reports2045-23222025-07-0115111510.1038/s41598-025-10036-8Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancementAya I. ELKasaby0Khalid M. Ghoneem1Yasser M. Shabana2Faculty of Agriculture, Mansoura UniversitySeed Pathology Research Department, Plant Pathology Research Institute, Agricultural Research CenterFaculty of Agriculture, Mansoura UniversityAbstract Onion white rot, caused by Stromatinia cepivora, is a major soil-borne fungal disease that severely affects onion production. This study introduces a novel endophytic bacterium, Achromobacter xylosoxidans AX77 16S, isolated from healthy onion seeds, as a potential biocontrol agent and growth promoter. Out of 78 bacterial isolates screened, AX77 16S showed the strongest antifungal activity, inhibiting pathogen growth by 50% in dual culture assays. Its application significantly enhanced seed germination (up to 82%) and improved shoot and root development, increasing vigor indices by over 100% compared to untreated controls. The strain was identified by biochemical and molecular techniques and registered in GenBank (ON679518). GC–MS analysis revealed ten bioactive compounds in the bacterial filtrate, while scanning electron microscopy confirmed its damaging effects on fungal structures. Additionally, AX77 16S was formulated into a granular product that remained viable for up to one year. This study presents a promising, sustainable, and cost-effective alternative to chemical fungicides for managing onion white rot and promoting crop growth.https://doi.org/10.1038/s41598-025-10036-8Biological controlEndophytic bacteriaMicrobiotaOnionWhite rotStromatinia cepivora
spellingShingle Aya I. ELKasaby
Khalid M. Ghoneem
Yasser M. Shabana
Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
Scientific Reports
Biological control
Endophytic bacteria
Microbiota
Onion
White rot
Stromatinia cepivora
title Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
title_full Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
title_fullStr Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
title_full_unstemmed Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
title_short Development of a granular bioformulation of Achromobacter xylosoxidans AX77 16S for sustainable onion white rot management and growth enhancement
title_sort development of a granular bioformulation of achromobacter xylosoxidans ax77 16s for sustainable onion white rot management and growth enhancement
topic Biological control
Endophytic bacteria
Microbiota
Onion
White rot
Stromatinia cepivora
url https://doi.org/10.1038/s41598-025-10036-8
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