Molecular detection of DHFR gene polymorphisms in Pneumocystis jirovecii isolates from Indian patients

Molecular detection of DHFR gene polymorphisms in Pneumocystis jirovecii isolates from Indian patients

Introduction: Pneumocystis pneumonia (PCP) is an opportunistic life-threatening infection, especially for immunocompromised individuals. A trimethoprim-sulfamethoxazole (TMP-SMX) combination is commonly used for the treatment of PCP, targeting both dihydrofolate reductase (DHFR) and dihydropteroate...

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Main Authors: Yogita Singh, Bijay Ranjan Mirdha, Randeep Guleria, Shehla Khalil, Ashutosh Panda, Rama Chaudhry, Anant Mohan, Sushil Kumar Kabra, Lalit Kumar, Sanjay Kumar Agarwal
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2015-11-01
Series:Journal of Infection in Developing Countries
Subjects:
Pneumocystis jirovecii
dihydrofolate reductase
trimethoprim-sulfamethoxazole
polymorphisms
Online Access:https://jidc.org/index.php/journal/article/view/6810
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