Adherent junctions: Physiology, role in hydrocephalus and potential therapeutic targets

Adherent junctions: Physiology, role in hydrocephalus and potential therapeutic targets

In all epithelial cells, the adherent junctions (AJs) with cadherin as the core play an important role in the maintenance of the connection and the formation of apical-basal polarity. The ependymal cells close to the ventricular system rely on AJs with N-cadherin at the core to maintain their normal...

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Bibliographic Details
Main Authors: Zhiye Chen, Jian He, Yating Guo, Yue Hao, Wentao Lv, Zexin Chen, Junqiang Wang, Yijian Yang, Kaiyue Wang, Zhikun Liu, Qian Ouyang, Zhangjie Su, Pingsheng Hu, Gelei Xiao
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:IBRO Neuroscience Reports
Subjects:
Adherent junctions
Hydrocephalus
Cilia
CSF
Ependymal cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2667242125000211
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