The complement system in pregnant women with severe preeclampsia
Here, we discuss current theories regarding preeclampsia (PE) pathogenesis, a role of the complement system in PE onset and evaluate an impact of altered complement system on pregnancy outcomes and PE severity. The studies conducted in the field of preeclampsia have indeed raised numerous new scient...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2025-07-01
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| Series: | Акушерство, гинекология и репродукция |
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| Online Access: | https://www.gynecology.su/jour/article/view/2496 |
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| author | A. S. Antonova J. Kh. Khizroeva I. S. Kalashnikova M. V. Tretyakova Yu. A. Popyonova N. F. Kuneshko L. S. Fatkullina |
| author_facet | A. S. Antonova J. Kh. Khizroeva I. S. Kalashnikova M. V. Tretyakova Yu. A. Popyonova N. F. Kuneshko L. S. Fatkullina |
| author_sort | A. S. Antonova |
| collection | DOAJ |
| description | Here, we discuss current theories regarding preeclampsia (PE) pathogenesis, a role of the complement system in PE onset and evaluate an impact of altered complement system on pregnancy outcomes and PE severity. The studies conducted in the field of preeclampsia have indeed raised numerous new scientific questions and hypotheses. One of the key questions is whether the complement system activation is the primary PE cause or just a consequence of one or more pathological processes linked to this syndrome. |
| format | Article |
| id | doaj-art-d2032c65b55147a59bfb21407e6eb495 |
| institution | DOAJ |
| issn | 2313-7347 2500-3194 |
| language | Russian |
| publishDate | 2025-07-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Акушерство, гинекология и репродукция |
| spelling | doaj-art-d2032c65b55147a59bfb21407e6eb4952025-08-20T03:19:14ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942025-07-0119344345210.17749/2313-7347/ob.gyn.rep.2025.626988The complement system in pregnant women with severe preeclampsiaA. S. Antonova0J. Kh. Khizroeva1I. S. Kalashnikova2M. V. Tretyakova3Yu. A. Popyonova4N. F. Kuneshko5L. S. Fatkullina6Sechenov UniversitySechenov UniversitySechenov UniversitySechenov UniversityVorokhobov City Clinical Hospital № 67, Moscow Healthcare DepartmentCenter for Family Planning and Reproduction, Moscow Healthcare DepartmentKazan State Medical University, Ministry of Health of the Russian FederationHere, we discuss current theories regarding preeclampsia (PE) pathogenesis, a role of the complement system in PE onset and evaluate an impact of altered complement system on pregnancy outcomes and PE severity. The studies conducted in the field of preeclampsia have indeed raised numerous new scientific questions and hypotheses. One of the key questions is whether the complement system activation is the primary PE cause or just a consequence of one or more pathological processes linked to this syndrome.https://www.gynecology.su/jour/article/view/2496arterial hypertensionproteinuriapreeclampsiaреcomplement systemsevere preeclampsiacomplement system biomarkerspathogenesissystemic inflammatory responsehumoral immunity |
| spellingShingle | A. S. Antonova J. Kh. Khizroeva I. S. Kalashnikova M. V. Tretyakova Yu. A. Popyonova N. F. Kuneshko L. S. Fatkullina The complement system in pregnant women with severe preeclampsia Акушерство, гинекология и репродукция arterial hypertension proteinuria preeclampsia ре complement system severe preeclampsia complement system biomarkers pathogenesis systemic inflammatory response humoral immunity |
| title | The complement system in pregnant women with severe preeclampsia |
| title_full | The complement system in pregnant women with severe preeclampsia |
| title_fullStr | The complement system in pregnant women with severe preeclampsia |
| title_full_unstemmed | The complement system in pregnant women with severe preeclampsia |
| title_short | The complement system in pregnant women with severe preeclampsia |
| title_sort | complement system in pregnant women with severe preeclampsia |
| topic | arterial hypertension proteinuria preeclampsia ре complement system severe preeclampsia complement system biomarkers pathogenesis systemic inflammatory response humoral immunity |
| url | https://www.gynecology.su/jour/article/view/2496 |
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