The complement system in pregnant women with severe preeclampsia

The complement system in pregnant women with severe preeclampsia

Here, we discuss current theories regarding preeclampsia (PE) pathogenesis, a role of the complement system in PE onset and evaluate an impact of altered complement system on pregnancy outcomes and PE severity. The studies conducted in the field of preeclampsia have indeed raised numerous new scient...

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Bibliographic Details
Main Authors: A. S. Antonova, J. Kh. Khizroeva, I. S. Kalashnikova, M. V. Tretyakova, Yu. A. Popyonova, N. F. Kuneshko, L. S. Fatkullina
Format: Article
Language:Russian
Published: IRBIS LLC 2025-07-01
Series:Акушерство, гинекология и репродукция
Subjects:
arterial hypertension
proteinuria
preeclampsia
ре
complement system
severe preeclampsia
complement system biomarkers
pathogenesis
systemic inflammatory response
humoral immunity
Online Access:https://www.gynecology.su/jour/article/view/2496
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Summary:Here, we discuss current theories regarding preeclampsia (PE) pathogenesis, a role of the complement system in PE onset and evaluate an impact of altered complement system on pregnancy outcomes and PE severity. The studies conducted in the field of preeclampsia have indeed raised numerous new scientific questions and hypotheses. One of the key questions is whether the complement system activation is the primary PE cause or just a consequence of one or more pathological processes linked to this syndrome.
ISSN:2313-7347
2500-3194

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