Neurosyphilis: A rare cause of encephalitis in a young male
Acute neurosyphilis is a rare but easily treatable cause of subacute confusion. Its clinical presentation is varied, with reported phenotypes ranging from acute stroke-like presentations to psychosis, dementia and meningoencephalitis. Neurosyphilis is easily detectable and treatable, despite its cli...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-05-01
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| Series: | Clinical Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1470211825000302 |
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| Summary: | Acute neurosyphilis is a rare but easily treatable cause of subacute confusion. Its clinical presentation is varied, with reported phenotypes ranging from acute stroke-like presentations to psychosis, dementia and meningoencephalitis. Neurosyphilis is easily detectable and treatable, despite its clinical heterogeneity. We present a 45-year-old man without HIV presenting with a subacute encephalitis, with cerebrospinal fluid and blood markers strongly positive for syphilis, with clinical improvement following 2 weeks of empirical intravenous antibiotic therapy. |
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| ISSN: | 1470-2118 |