Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort

Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort

Abstract Background Plasma biomarkers offer a promising alternative to amyloid beta (Aβ) positron emission tomography (PET) or cerebrospinal fluid (CSF) biomarkers for diagnosing Alzheimer’s disease (AD). This cross-sectional study assessed the utility of multiple plasma biomarkers for diagnosing an...

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Main Authors: Masahito Kubota, Shogyoku Bun, Keisuke Takahata, Shin Kurose, Yuki Momota, Yu Iwabuchi, Toshiki Tezuka, Hajime Tabuchi, Morinobu Seki, Yasuharu Yamamoto, Ryo Shikimoto, Yu Mimura, Takayuki Hoshino, Sho Shimohama, Natsumi Suzuki, Ayaka Morimoto, Azusa Oosumi, Yuka Hoshino, Kenji Tai, Hirofumi Aoyagi, Yoshiaki Sato, Junro Kuromitsu, Jin Nakahara, Masaru Mimura, Daisuke Ito
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Plasma biomarkers
Aβ42/40
p-tau217
p-tau217/Aβ42
HISCL
Online Access:https://doi.org/10.1186/s13195-025-01778-8
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