Tea and depression
ABSTRACT: The available evidence, which derives from studies investigating mechanistic effects of tea, research on animal models as well as epidemiological studies and intervention trials in humans, suggests that compounds contained in tea may have the potential to aid in the prevention of depressio...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2022-05-01
|
| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453021001609 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832557405347512320 |
|---|---|
| author | Klaus W. Lange Yukiko Nakamura Katharina M. Lange Hui Zhao |
| author_facet | Klaus W. Lange Yukiko Nakamura Katharina M. Lange Hui Zhao |
| author_sort | Klaus W. Lange |
| collection | DOAJ |
| description | ABSTRACT: The available evidence, which derives from studies investigating mechanistic effects of tea, research on animal models as well as epidemiological studies and intervention trials in humans, suggests that compounds contained in tea may have the potential to aid in the prevention of depression or in its treatment as an addition to established therapies. A wide range of potentially antidepressive biological activities of tea components have been reported. However, the mechanisms of tea phytochemicals possibly capable of decreasing the risk of depressive symptoms are complex, multifaceted and not well understood. Potent pharmacological effects on circumscribed neurobiological systems may be produced not by individual tea components but rather by the synergistic action of various compounds on multiple pathophysiological mechanisms involved in depression. While epidemiological studies have generally demonstrated beneficial effects of tea consumption on mood and depressive symptoms, cross-sectional studies are unable to prove a cause-effect relationship. If positive effects on mood could be firmly established, tea drinking could support mental health. However, the moderate antidepressive effects observed in healthy people are not necessarily indicative of possible clinical effects in major depressive disorder. Randomized controlled intervention studies are needed to establish a causal relationship between bioactive compounds in tea and depression. |
| format | Article |
| id | doaj-art-d1e8d1803705479f93c4a3474ac46219 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2022-05-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-d1e8d1803705479f93c4a3474ac462192025-02-03T05:14:30ZengTsinghua University PressFood Science and Human Wellness2213-45302022-05-01113476482Tea and depressionKlaus W. Lange0Yukiko Nakamura1Katharina M. Lange2Hui Zhao3Department of Experimental Psychology, University of Regensburg, Regensburg 93040, Germany; Correspondence: Institute of Psychology, University of Regensburg, Regensburg 93040, Germany.Department of Experimental Psychology, University of Regensburg, Regensburg 93040, GermanyDepartment of Experimental Psychology, University of Regensburg, Regensburg 93040, GermanyTianjin Key Laboratory of Food and Biotechnology, University of Commerce, Tianjin 300134, ChinaABSTRACT: The available evidence, which derives from studies investigating mechanistic effects of tea, research on animal models as well as epidemiological studies and intervention trials in humans, suggests that compounds contained in tea may have the potential to aid in the prevention of depression or in its treatment as an addition to established therapies. A wide range of potentially antidepressive biological activities of tea components have been reported. However, the mechanisms of tea phytochemicals possibly capable of decreasing the risk of depressive symptoms are complex, multifaceted and not well understood. Potent pharmacological effects on circumscribed neurobiological systems may be produced not by individual tea components but rather by the synergistic action of various compounds on multiple pathophysiological mechanisms involved in depression. While epidemiological studies have generally demonstrated beneficial effects of tea consumption on mood and depressive symptoms, cross-sectional studies are unable to prove a cause-effect relationship. If positive effects on mood could be firmly established, tea drinking could support mental health. However, the moderate antidepressive effects observed in healthy people are not necessarily indicative of possible clinical effects in major depressive disorder. Randomized controlled intervention studies are needed to establish a causal relationship between bioactive compounds in tea and depression.http://www.sciencedirect.com/science/article/pii/S2213453021001609DepressionTeaL-theaninePreventionTreatment |
| spellingShingle | Klaus W. Lange Yukiko Nakamura Katharina M. Lange Hui Zhao Tea and depression Food Science and Human Wellness Depression Tea L-theanine Prevention Treatment |
| title | Tea and depression |
| title_full | Tea and depression |
| title_fullStr | Tea and depression |
| title_full_unstemmed | Tea and depression |
| title_short | Tea and depression |
| title_sort | tea and depression |
| topic | Depression Tea L-theanine Prevention Treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2213453021001609 |
| work_keys_str_mv | AT klauswlange teaanddepression AT yukikonakamura teaanddepression AT katharinamlange teaanddepression AT huizhao teaanddepression |