Disease probability-enhanced follow-up chest X-ray radiology report summary generation

Abstract A chest X-ray radiology report describes abnormal findings not only from X-ray obtained at a given examination, but also findings on disease progression or change in device placement with reference to the X-ray from previous examination. Majority of the efforts on automatic generation of ra...

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Main Authors: Zhichuan Wang, Qiao Deng, Tiffany Y. So, Wan Hang Chiu, Kinhei Lee, Edward S. Hui
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-12684-2
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author Zhichuan Wang
Qiao Deng
Tiffany Y. So
Wan Hang Chiu
Kinhei Lee
Edward S. Hui
author_facet Zhichuan Wang
Qiao Deng
Tiffany Y. So
Wan Hang Chiu
Kinhei Lee
Edward S. Hui
author_sort Zhichuan Wang
collection DOAJ
description Abstract A chest X-ray radiology report describes abnormal findings not only from X-ray obtained at a given examination, but also findings on disease progression or change in device placement with reference to the X-ray from previous examination. Majority of the efforts on automatic generation of radiology report pertain to reporting the former, but not the latter, type of findings. To the best of the authors’ knowledge, there is only one work dedicated to generating summary of the latter findings, i.e., follow-up radiology report summary. In this study, we propose a transformer-based framework to tackle this task. Motivated by our observations on the significance of medical lexicon on the fidelity of report summary generation, we introduce two mechanisms to bestow clinical insight to our model, namely disease probability soft guidance and masked entity modeling loss. The former mechanism employs a pretrained abnormality classifier to guide the presence level of specific abnormalities, while the latter directs the model’s attention toward medical lexicon. Extensive experiments were conducted to demonstrate that the performance of our model exceeded the state-of-the-art.
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institution Kabale University
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publishDate 2025-07-01
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spelling doaj-art-d1db4f32f63c4b0aabc78aaa07fecf8b2025-08-20T04:02:46ZengNature PortfolioScientific Reports2045-23222025-07-0115111210.1038/s41598-025-12684-2Disease probability-enhanced follow-up chest X-ray radiology report summary generationZhichuan Wang0Qiao Deng1Tiffany Y. So2Wan Hang Chiu3Kinhei Lee4Edward S. Hui5Department of Imaging and Interventional Radiology, The Chinese University of Hong KongDepartment of Imaging and Interventional Radiology, The Chinese University of Hong KongDepartment of Imaging and Interventional Radiology, The Chinese University of Hong KongHospital AuthorityDepartment of Imaging and Interventional Radiology, The Chinese University of Hong KongDepartment of Imaging and Interventional Radiology, The Chinese University of Hong KongAbstract A chest X-ray radiology report describes abnormal findings not only from X-ray obtained at a given examination, but also findings on disease progression or change in device placement with reference to the X-ray from previous examination. Majority of the efforts on automatic generation of radiology report pertain to reporting the former, but not the latter, type of findings. To the best of the authors’ knowledge, there is only one work dedicated to generating summary of the latter findings, i.e., follow-up radiology report summary. In this study, we propose a transformer-based framework to tackle this task. Motivated by our observations on the significance of medical lexicon on the fidelity of report summary generation, we introduce two mechanisms to bestow clinical insight to our model, namely disease probability soft guidance and masked entity modeling loss. The former mechanism employs a pretrained abnormality classifier to guide the presence level of specific abnormalities, while the latter directs the model’s attention toward medical lexicon. Extensive experiments were conducted to demonstrate that the performance of our model exceeded the state-of-the-art.https://doi.org/10.1038/s41598-025-12684-2
spellingShingle Zhichuan Wang
Qiao Deng
Tiffany Y. So
Wan Hang Chiu
Kinhei Lee
Edward S. Hui
Disease probability-enhanced follow-up chest X-ray radiology report summary generation
Scientific Reports
title Disease probability-enhanced follow-up chest X-ray radiology report summary generation
title_full Disease probability-enhanced follow-up chest X-ray radiology report summary generation
title_fullStr Disease probability-enhanced follow-up chest X-ray radiology report summary generation
title_full_unstemmed Disease probability-enhanced follow-up chest X-ray radiology report summary generation
title_short Disease probability-enhanced follow-up chest X-ray radiology report summary generation
title_sort disease probability enhanced follow up chest x ray radiology report summary generation
url https://doi.org/10.1038/s41598-025-12684-2
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