Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments

<p>Background: Many studies have been conducted in Italy to assess Health-Related Quality-of-Life (HRQoL) in subjects with different diseases. However, no recent HRQoL population norm data were available to make comparisons with diseased populations. We assessed HRQoL norm data using the gener...

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Main Authors: Luciana Scalone, Paolo Angelo Cortesi, Roberta Ciampichini, Giancarlo Cesana, Lorenzo Giovanni Mantovani
Format: Article
Language:English
Published: Milano University Press 2015-09-01
Series:Epidemiology, Biostatistics and Public Health
Online Access:http://ebph.it/article/view/11457
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author Luciana Scalone
Paolo Angelo Cortesi
Roberta Ciampichini
Giancarlo Cesana
Lorenzo Giovanni Mantovani
author_facet Luciana Scalone
Paolo Angelo Cortesi
Roberta Ciampichini
Giancarlo Cesana
Lorenzo Giovanni Mantovani
author_sort Luciana Scalone
collection DOAJ
description <p>Background: Many studies have been conducted in Italy to assess Health-Related Quality-of-Life (HRQoL) in subjects with different diseases. However, no recent HRQoL population norm data were available to make comparisons with diseased populations. We assessed HRQoL norm data using the generic instrument EQ-5D in its standard version (EQ-5D-3L) and with the recently introduced version (EQ-5D-5L).</p><p>Methods: A survey was conducted on 6,800 individuals representative of the Lombardy general adult population for age, gender and geographical distribution. Each participant underwent a telephone interview with questions using the EQ-5D-3L and the EQ-5D-5L descriptive systems, the visual analogue scale (EQ-VAS) and socio-demographic data.</p><p>Results: participants were 48% male, aged on average 51.9 years. With the 3L version, men and women aged 18-35 years reporting a full health state were 71.3% and 56.5%, respectively, those aged <span>&gt;</span>76 years decreased to 29.5% and 13.5%, respectively. The proportion of respondents reporting no problems decreased with the 5L version. The mean (standard deviation) of the EQ-VAS was 87.7(12.1) and 85.0(15.2) among men and women aged 18-35 years, and 68.0(20.6) and 64.4(23.2) in men and women aged <span>&gt;</span>76 years. The mean (standard deviation) utility obtained from the 3L version ranged from 0.965(0.068) and 0.944(0.086) among men and women aged 18-35 years, to 0.880(0.123) and 0.829(0.137) in men and women aged <span>&gt;</span>76 years. Similar results were obtained with the 5L version.</p><p>Conclusion: HRQoL norm data are now available from the Italian general adult population, to be used as a reference in clinical sector, economic evaluations and in policy setting.</p>
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spelling doaj-art-d1c0a23ea29d4979acbe6ae07eb0b3ba2025-08-20T02:19:42ZengMilano University PressEpidemiology, Biostatistics and Public Health2282-09302015-09-0112310.2427/1145710535Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instrumentsLuciana Scalone0Paolo Angelo CortesiRoberta CiampichiniGiancarlo CesanaLorenzo Giovanni Mantovani1) Research Centre of Public Health (CESP), University of Milano-Bicocca, Monza, Italy, 2) CHARTA Foundation, Milan, Italy<p>Background: Many studies have been conducted in Italy to assess Health-Related Quality-of-Life (HRQoL) in subjects with different diseases. However, no recent HRQoL population norm data were available to make comparisons with diseased populations. We assessed HRQoL norm data using the generic instrument EQ-5D in its standard version (EQ-5D-3L) and with the recently introduced version (EQ-5D-5L).</p><p>Methods: A survey was conducted on 6,800 individuals representative of the Lombardy general adult population for age, gender and geographical distribution. Each participant underwent a telephone interview with questions using the EQ-5D-3L and the EQ-5D-5L descriptive systems, the visual analogue scale (EQ-VAS) and socio-demographic data.</p><p>Results: participants were 48% male, aged on average 51.9 years. With the 3L version, men and women aged 18-35 years reporting a full health state were 71.3% and 56.5%, respectively, those aged <span>&gt;</span>76 years decreased to 29.5% and 13.5%, respectively. The proportion of respondents reporting no problems decreased with the 5L version. The mean (standard deviation) of the EQ-VAS was 87.7(12.1) and 85.0(15.2) among men and women aged 18-35 years, and 68.0(20.6) and 64.4(23.2) in men and women aged <span>&gt;</span>76 years. The mean (standard deviation) utility obtained from the 3L version ranged from 0.965(0.068) and 0.944(0.086) among men and women aged 18-35 years, to 0.880(0.123) and 0.829(0.137) in men and women aged <span>&gt;</span>76 years. Similar results were obtained with the 5L version.</p><p>Conclusion: HRQoL norm data are now available from the Italian general adult population, to be used as a reference in clinical sector, economic evaluations and in policy setting.</p>http://ebph.it/article/view/11457
spellingShingle Luciana Scalone
Paolo Angelo Cortesi
Roberta Ciampichini
Giancarlo Cesana
Lorenzo Giovanni Mantovani
Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
Epidemiology, Biostatistics and Public Health
title Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
title_full Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
title_fullStr Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
title_full_unstemmed Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
title_short Health Related Quality of Life norm data of the Italian general population: results using the EQ-5D-3L and EQ-5D-5L instruments
title_sort health related quality of life norm data of the italian general population results using the eq 5d 3l and eq 5d 5l instruments
url http://ebph.it/article/view/11457
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