Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications
Hydroxyapatite nanoparticles (HANPs) are becoming increasingly crucial in dental implant applications as they are highly compatible with biological systems, actively support biological processes, and closely resemble bone minerals. This review covers the latest progress in how HANPs are made, studie...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-06-01
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| Series: | International Dental Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0020653924016150 |
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| author | Md. Aminul Islam Nayem Hossain Sumaya Hossain Fardin Khan Saniya Hossain Md. Mostafizur Rahman Arup Mohammad Asaduzzaman Chowdhury Md. Majibur Rahman |
| author_facet | Md. Aminul Islam Nayem Hossain Sumaya Hossain Fardin Khan Saniya Hossain Md. Mostafizur Rahman Arup Mohammad Asaduzzaman Chowdhury Md. Majibur Rahman |
| author_sort | Md. Aminul Islam |
| collection | DOAJ |
| description | Hydroxyapatite nanoparticles (HANPs) are becoming increasingly crucial in dental implant applications as they are highly compatible with biological systems, actively support biological processes, and closely resemble bone minerals. This review covers the latest progress in how HANPs are made, studied, and used in dentistry. It looks at critical methods for creating HANPs, such as sol-gel, microwave hydrothermal synthesis, and biomimetic approaches, and how they affect the particles' size, structure, and activity. The green synthesis method illustrated a new door to synthesize HAp for maintaining biocompatibilityand increasing antibacterial properties. The review also explores how HANPs improve the integration of implants with bone, support bone growth, and help treat sensitive teeth based on various laboratory and clinical studies. The usage of HAp in dentin and enamel shows higher potentiality through FTIR, XPS, XRD, EDS, etc., for mechanical stability and biological balance compared to natural teeth. Additionally, the use of HANPs in dental products like toothpaste and mouthwash is discussed, highlighting its potential to help rebuild tooth enamel and fight bacteria. There are some challenges for long-term usage against oral bacteria, but doping with inorganic materials, like Zn, has already solved this periodontal problem. Much more research is still essential to estimate the fabrication variation based on patient problems and characteristics. Still, it has favorable outcomes regarding its bioactive nature and antimicrobial properties. Due to their compatibility with biological tissues and ability to support bone growth, HANPs hold great promise for advancing dental materials and implant technology, potentially leading to better dental care and patient outcomes. |
| format | Article |
| id | doaj-art-d1bac6b78c3c42dbb69007bf82da292b |
| institution | OA Journals |
| issn | 0020-6539 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Dental Journal |
| spelling | doaj-art-d1bac6b78c3c42dbb69007bf82da292b2025-08-20T01:49:08ZengElsevierInternational Dental Journal0020-65392025-06-017532272231310.1016/j.identj.2024.11.020Advances of Hydroxyapatite Nanoparticles in Dental Implant ApplicationsMd. Aminul Islam0Nayem Hossain1Sumaya Hossain2Fardin Khan3Saniya Hossain4Md. Mostafizur Rahman Arup5Mohammad Asaduzzaman Chowdhury6Md. Majibur Rahman7Department of Mechanical Engineering, International University of Business Agriculture and Technology, Dhaka, Dhaka, BangladeshDepartment of Mechanical Engineering, International University of Business Agriculture and Technology, Dhaka, Dhaka, Bangladesh; Corresponding author. Department of Mechanical Engineering, International University of Business Agriculture and Technology, Dhaka, Dhaka, 1230, Bangladesh.Department of Pharmacy, Primeasia University, Dhaka, Dhaka, BangladeshDepartment of Mechanical Engineering, International University of Business Agriculture and Technology, Dhaka, Dhaka, BangladeshDepartment of Microbiology, Jashore University of Science and Technology, Jessore, Jessore, BangladeshDepartment of Mechanical Engineering, International University of Business Agriculture and Technology, Dhaka, Dhaka, BangladeshDepartment of Mechanical Engineering, Dhaka University of Engineering and Technology, Gazipur, Gazipur, BangladeshDepartment of Microbiology, University of Dhaka, Dhaka, Dhaka, BangladeshHydroxyapatite nanoparticles (HANPs) are becoming increasingly crucial in dental implant applications as they are highly compatible with biological systems, actively support biological processes, and closely resemble bone minerals. This review covers the latest progress in how HANPs are made, studied, and used in dentistry. It looks at critical methods for creating HANPs, such as sol-gel, microwave hydrothermal synthesis, and biomimetic approaches, and how they affect the particles' size, structure, and activity. The green synthesis method illustrated a new door to synthesize HAp for maintaining biocompatibilityand increasing antibacterial properties. The review also explores how HANPs improve the integration of implants with bone, support bone growth, and help treat sensitive teeth based on various laboratory and clinical studies. The usage of HAp in dentin and enamel shows higher potentiality through FTIR, XPS, XRD, EDS, etc., for mechanical stability and biological balance compared to natural teeth. Additionally, the use of HANPs in dental products like toothpaste and mouthwash is discussed, highlighting its potential to help rebuild tooth enamel and fight bacteria. There are some challenges for long-term usage against oral bacteria, but doping with inorganic materials, like Zn, has already solved this periodontal problem. Much more research is still essential to estimate the fabrication variation based on patient problems and characteristics. Still, it has favorable outcomes regarding its bioactive nature and antimicrobial properties. Due to their compatibility with biological tissues and ability to support bone growth, HANPs hold great promise for advancing dental materials and implant technology, potentially leading to better dental care and patient outcomes.http://www.sciencedirect.com/science/article/pii/S0020653924016150HydroxyapatiteImplantBone regenerationBiodegradationDental treatments |
| spellingShingle | Md. Aminul Islam Nayem Hossain Sumaya Hossain Fardin Khan Saniya Hossain Md. Mostafizur Rahman Arup Mohammad Asaduzzaman Chowdhury Md. Majibur Rahman Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications International Dental Journal Hydroxyapatite Implant Bone regeneration Biodegradation Dental treatments |
| title | Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications |
| title_full | Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications |
| title_fullStr | Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications |
| title_full_unstemmed | Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications |
| title_short | Advances of Hydroxyapatite Nanoparticles in Dental Implant Applications |
| title_sort | advances of hydroxyapatite nanoparticles in dental implant applications |
| topic | Hydroxyapatite Implant Bone regeneration Biodegradation Dental treatments |
| url | http://www.sciencedirect.com/science/article/pii/S0020653924016150 |
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