Comprehensive characterization of T cell subtypes in lung adenocarcinoma: Prognostic, predictive, and therapeutic implications

Comprehensive characterization of T cell subtypes in lung adenocarcinoma: Prognostic, predictive, and therapeutic implications

Background: T cells are crucial for immunosurveillance and tumor eradication, with their dysregulation or absence in the tumor microenvironment linked to immunotherapy resistance. In lung adenocarcinoma (LUAD), this resistance is a significant barrier to effective treatment, highlighting the need fo...

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Bibliographic Details
Main Authors: Shiquan Liu, Hao Sun, Tianye Song, Ce Liang, Lele Deng, Haiyong Zhu, Fangchao Zhao, Shujun Li
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Translational Oncology
Subjects:
Single-cell RNA sequencing
T cell
Lung adenocarcinoma
Tumor immune environment
Prognostic risk model
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000634
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