Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

Targeting fibroblast activation protein in rheumatoid arthritis: from molecular imaging to precision therapeutics

Rheumatoid arthritis (RA), a chronic inflammatory disorder characterized by synovitis and joint destruction, remains a global health challenge. Activated fibroblast-like synoviocytes (FLS), which play a crucial role in the progression of RA, demonstrate tumor-like invasiveness and secrete inflammato...

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Bibliographic Details
Main Authors: Yupeng Huang, Yang Wu, Huan Liu, Yuehong Chen, Qibing Xie, Geng Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
fibroblast activation protein
FAPI
disease evaluation
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616618/full
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