Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery
[Objective] To investigate the effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during anesthesia induction in elderly patients undergoing laparoscopic surgery. [Methods] 116 elderly patients undergoing elective laparoscopic surgery in Yibin Hospital, West China...
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Editorial Office of International Journal of Geriatrics
2025-05-01
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| Series: | Guoji laonian yixue zazhi |
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| Online Access: | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.03.009&lang=en |
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| author | Zou Qi Chen Min Liu Jinghua |
| author_facet | Zou Qi Chen Min Liu Jinghua |
| author_sort | Zou Qi |
| collection | DOAJ |
| description | [Objective] To investigate the effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during anesthesia induction in elderly patients undergoing laparoscopic surgery. [Methods] 116 elderly patients undergoing elective laparoscopic surgery in Yibin Hospital, West China Hospital, Sichuan University from December 2022 to March 2024 were selected as the study subjects and divided into observation group and control group according to random number table, with 58 cases in each group. Remazolam was used for anesthesia induction and maintenance in the observation group, and Propofol was used for anesthesia induction and maintenance in the control group. The hemodynamic indicators and the quality of recovery at two different time points were compared, and the occurrence of adverse reactions and cognitive function scores were recorded. [Results] In the observation group, the heart rate and mean arterial pressure immediately after tracheal intubation and 3 min after intubation were higher than those in the control group (P<0.05), the spontaneous respiratory recovery time, eye-opening time and extubation time were shorter than those in the control group (P<0.05), the cognitive function scores at 1 d and 3 d after operation were higher than those in the control group (P<0.05)，the total incidence of adverse reactions was lower than that in the control group (P<0.05). [Conclusion] Compared with Propofol, Remazolam is used in elderly laparoscopic surgery, with more stable intraoperative blood flow fluctuations, faster postoperative recovery, and fewer adverse reactions. For patients with less cognitive function, it is suitable for elderly patients with relatively weak body and easily unstable hemodynamics. |
| format | Article |
| id | doaj-art-d18c97a9bf4748d5830bfd0f4fa0cf47 |
| institution | Kabale University |
| issn | 1674-7593 |
| language | zho |
| publishDate | 2025-05-01 |
| publisher | Editorial Office of International Journal of Geriatrics |
| record_format | Article |
| series | Guoji laonian yixue zazhi |
| spelling | doaj-art-d18c97a9bf4748d5830bfd0f4fa0cf472025-08-20T03:53:51ZzhoEditorial Office of International Journal of GeriatricsGuoji laonian yixue zazhi1674-75932025-05-0146330831210.3969/j.issn.1674-7593.2025.03.009Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgeryZou Qi0Chen Min1Liu Jinghua2Department of Anesthesiology, Yibin Hospital, West China Hospital, Sichuan University, Yibin 644000Department of Anesthesiology, Yibin Hospital, West China Hospital, Sichuan University, Yibin 644000Department of Anesthesiology, Yibin Hospital, West China Hospital, Sichuan University, Yibin 644000[Objective] To investigate the effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during anesthesia induction in elderly patients undergoing laparoscopic surgery. [Methods] 116 elderly patients undergoing elective laparoscopic surgery in Yibin Hospital, West China Hospital, Sichuan University from December 2022 to March 2024 were selected as the study subjects and divided into observation group and control group according to random number table, with 58 cases in each group. Remazolam was used for anesthesia induction and maintenance in the observation group, and Propofol was used for anesthesia induction and maintenance in the control group. The hemodynamic indicators and the quality of recovery at two different time points were compared, and the occurrence of adverse reactions and cognitive function scores were recorded. [Results] In the observation group, the heart rate and mean arterial pressure immediately after tracheal intubation and 3 min after intubation were higher than those in the control group (P<0.05), the spontaneous respiratory recovery time, eye-opening time and extubation time were shorter than those in the control group (P<0.05), the cognitive function scores at 1 d and 3 d after operation were higher than those in the control group (P<0.05)，the total incidence of adverse reactions was lower than that in the control group (P<0.05). [Conclusion] Compared with Propofol, Remazolam is used in elderly laparoscopic surgery, with more stable intraoperative blood flow fluctuations, faster postoperative recovery, and fewer adverse reactions. For patients with less cognitive function, it is suitable for elderly patients with relatively weak body and easily unstable hemodynamics.http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.03.009&lang=enremazolampropofollaparoscopic surgeryhemodynamicscognitive function |
| spellingShingle | Zou Qi Chen Min Liu Jinghua Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery Guoji laonian yixue zazhi remazolam propofol laparoscopic surgery hemodynamics cognitive function |
| title | Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| title_full | Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| title_fullStr | Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| title_full_unstemmed | Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| title_short | Effects of Remazolam and Propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| title_sort | effects of remazolam and propofol on hemodynamics and postoperative cognitive function during induction of anesthesia in elderly patients undergoing laparoscopic surgery |
| topic | remazolam propofol laparoscopic surgery hemodynamics cognitive function |
| url | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.03.009&lang=en |
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