Unraveling drug resistance mechanisms in testicular cancer through immune cell phenotypes: a bidirectional Mendelian randomization analysis revealing novel therapeutic targets
Abstract Objective While testicular cancer is highly curable, drug resistance remains a challenge in relapsed or refractory cases. This study explores the immune system's role in resistance mechanisms via bidirectional Mendelian Randomization (MR) analysis of 731 immune cell phenotypes. Method...
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| Main Authors: | Lin Xiao, Tianen Wu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
|
| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02757-z |
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