Efficient secretory expression of human milk Osteopontin in Komagataella phaffii

Efficient secretory expression of human milk Osteopontin in Komagataella phaffii

Osteopontin (OPN), a bioactive milk protein in breast milk, has diverse applications in food and medicine. OPN is predominantly extracted from fresh bovine milk; however, the concentration of OPN in bovine milk is exceedingly low. To address these issues, in the present study, we used Komagataella p...

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Bibliographic Details
Main Authors: Zhihang Zhang, Yangyang Li, Zhenmin Liu, Shixiu Cui, Xianhao Xu, Yanfeng Liu, Jianghua Li, Guocheng Du, Xueqin Lv, Long Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Future Foods
Subjects:
Komagataella phaffii
Osteopontin
Hybrid signal peptide
Molecular chaperone
Secretory expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2666833524000996
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