Biomolecular phase separation in tumorigenesis: from aberrant condensates to therapeutic vulnerabilities
Abstract Biomolecular phase separation has emerged as a fundamental mechanism governing intracellular spatial organization and functional compartmentalization, and is increasingly recognized as a critical factor in tumor initiation and progression. Through multivalent molecular interactions, biomole...
Saved in:
| Main Authors: | Lan Hu, Zikun Huang, Zhaoyong Liu, Ying Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | Molecular Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12943-025-02428-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Liquid-liquid phase separation: an emerging perspective on the tumorigenesis, progression, and treatment of tumors
by: Qin Jian, et al.
Published: (2025-06-01) -
Liquid–liquid phase separation regulates gene expression in plants
by: Diyi Fu, et al.
Published: (2025-06-01) -
A computational pipeline for image-based statistical analysis of biomolecular condensates dynamics using morphological descriptors
by: Ivan Rosa e Silva, et al.
Published: (2025-07-01) -
An Overview of Liquid-Liquid Phase Separation and Its Mechanisms in Sepsis
by: Cao M, et al.
Published: (2025-03-01) -
Microphase separation produces interfacial environment within diblock biomolecular condensates
by: Andrew P Latham, et al.
Published: (2025-03-01)