Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries
Introduction: Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of child-bearing age and is associated with increased susceptibility to HIV-AIDS and sexually transmitted diseases. In obstetrics, BV has been implicated in causing various complications. In clinic...
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The Journal of Infection in Developing Countries
2011-11-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/1625 |
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| author | Vineeta Mittal Amita Jain Yashodhara Pradeep |
| author_facet | Vineeta Mittal Amita Jain Yashodhara Pradeep |
| author_sort | Vineeta Mittal |
| collection | DOAJ |
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Introduction: Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of child-bearing age and is associated with increased susceptibility to HIV-AIDS and sexually transmitted diseases. In obstetrics, BV has been implicated in causing various complications. In clinical practice, BV is diagnosed using Amsel criteria and Nugent scoring. Using modified Amsel criteria, we determined that the fulfilling of any two instead of three criteria can be diagnostic of BV.
Methodology: This prospective cross-sectional study involved pregnant females complaining of excessive vaginal discharge admitted in a tertiary health centre in central India. Four vaginal swabs were collected for the diagnosis of BV by Amsel criteria, modified Amsel criteria, and Nugent scoring on Gram stain. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of each individual criterion and combinations of criteria were calculated by using Nugent scoring as the gold standard and by chi square test.
Results: In the present study overall prevalence of BV was 12%. The sensitivity of individual or a combination of two criteria was almost same or higher than that of Amsel criteria. Specificity of each combination of criteria was comparable to that of Amsel criteria. However, a combination of high pH and amine odor test had the highest sensitivity (88%) and highest PPV (62%). Diagnostic accuracy of all combinations in our study was equal to or slightly higher than that of Amsel criteria.
Conclusion: Diagnostic accuracy of new modified Amsel criteria is as reliable as that of Amsel criteria.
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| format | Article |
| id | doaj-art-d16e84e0ab5942dbba53f4c0c426e3f0 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2011-11-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-d16e84e0ab5942dbba53f4c0c426e3f02025-08-20T02:27:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802011-11-0160510.3855/jidc.1625Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countriesVineeta Mittal0Amita Jain1Yashodhara Pradeep2Era’s Lucknow Medical College and Hospital, Lucknow, IndiaChhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical University), Lucknow, IndiaChhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical University), Lucknow, India Introduction: Bacterial vaginosis (BV) is the commonest cause of abnormal vaginal discharge in women of child-bearing age and is associated with increased susceptibility to HIV-AIDS and sexually transmitted diseases. In obstetrics, BV has been implicated in causing various complications. In clinical practice, BV is diagnosed using Amsel criteria and Nugent scoring. Using modified Amsel criteria, we determined that the fulfilling of any two instead of three criteria can be diagnostic of BV. Methodology: This prospective cross-sectional study involved pregnant females complaining of excessive vaginal discharge admitted in a tertiary health centre in central India. Four vaginal swabs were collected for the diagnosis of BV by Amsel criteria, modified Amsel criteria, and Nugent scoring on Gram stain. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of each individual criterion and combinations of criteria were calculated by using Nugent scoring as the gold standard and by chi square test. Results: In the present study overall prevalence of BV was 12%. The sensitivity of individual or a combination of two criteria was almost same or higher than that of Amsel criteria. Specificity of each combination of criteria was comparable to that of Amsel criteria. However, a combination of high pH and amine odor test had the highest sensitivity (88%) and highest PPV (62%). Diagnostic accuracy of all combinations in our study was equal to or slightly higher than that of Amsel criteria. Conclusion: Diagnostic accuracy of new modified Amsel criteria is as reliable as that of Amsel criteria. https://jidc.org/index.php/journal/article/view/1625Amsel criteriabacterial vaginosisBVNugent scoring |
| spellingShingle | Vineeta Mittal Amita Jain Yashodhara Pradeep Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries Journal of Infection in Developing Countries Amsel criteria bacterial vaginosis BV Nugent scoring |
| title | Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| title_full | Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| title_fullStr | Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| title_full_unstemmed | Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| title_short | Development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| title_sort | development of modified diagnostic criteria for bacterial vaginosis at peripheral health centres in developing countries |
| topic | Amsel criteria bacterial vaginosis BV Nugent scoring |
| url | https://jidc.org/index.php/journal/article/view/1625 |
| work_keys_str_mv | AT vineetamittal developmentofmodifieddiagnosticcriteriaforbacterialvaginosisatperipheralhealthcentresindevelopingcountries AT amitajain developmentofmodifieddiagnosticcriteriaforbacterialvaginosisatperipheralhealthcentresindevelopingcountries AT yashodharapradeep developmentofmodifieddiagnosticcriteriaforbacterialvaginosisatperipheralhealthcentresindevelopingcountries |