Impact of anti-VZV IgG levels on Parkinson’s disease risk and progression: a Mendelian randomization analysis

Impact of anti-VZV IgG levels on Parkinson’s disease risk and progression: a Mendelian randomization analysis

Abstract Research suggests a potential link between varicella zoster virus (VZV) and Parkinson’s disease (PD), but the causal relationship between anti-VZV IgG levels and PD is not well understood. Using two-sample Mendelian Randomization (MR), we assessed the causal impact of anti-VZV IgG levels on...

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Main Authors: Jinxing Sun, Xiangchen Li, Shengmei Ma, Haopeng Lin, Zhenke Li, Junheng Jia, Yasaman Alizadeh, Qianqian Wu, Ying Hou, Hong Wang, Qi Wang, Guangjian Zhang, Xingang Li, Weiguo Li, Chao Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Parkinson’s disease
Mendelian randomization
VZV
Anti-VZV IgG levels
Online Access:https://doi.org/10.1038/s41598-025-96382-z
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