A NEW COMBINATION INHIBITS INTESTINAL CHOLESTEROL ABSORPTION, SUPPRESSES ENDOGENOUS CHOLESTEROL SYNTHESIS, AND DEMONSTRATES ANTI-INFLAMMATORY AND HEPATOPROTECTIVE EFFECTS

A NEW COMBINATION INHIBITS INTESTINAL CHOLESTEROL ABSORPTION, SUPPRESSES ENDOGENOUS CHOLESTEROL SYNTHESIS, AND DEMONSTRATES ANTI-INFLAMMATORY AND HEPATOPROTECTIVE EFFECTS

Hypercholesterolemia (HCH) and vascular inflammation are the main therapeutic targets in atherosclerosis. The paper discusses the results of the studies which have focussed on the effects of a new class of physiologically active substances (polyprenols and β-sitosterols) on lipid profile and pro-inf...

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Bibliographic Details
Main Authors: R. G. Oganov, S. I. Chernova, V. Yu. Gorbacheva
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2013-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
atherosclerosis
inflammation
dyslipidaemia
pro-inflammatory cytokines
polyprenol phosphates
phytosterols
Online Access:https://cardiovascular.elpub.ru/jour/article/view/197
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Summary:Hypercholesterolemia (HCH) and vascular inflammation are the main therapeutic targets in atherosclerosis. The paper discusses the results of the studies which have focussed on the effects of a new class of physiologically active substances (polyprenols and β-sitosterols) on lipid profile and pro-inflammatory cytokines in HCH patients with low to moderate cardiovascular risk. Polyprenol phosphates and phytosterols could help to achieve significant changes in lipid profile and normalisation of immunologic parameters.
ISSN:1728-8800
2619-0125

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