Mechanisms of Keap1/Nrf2 modulation in bacterial infections: implications in persistence and clearance

Mechanisms of Keap1/Nrf2 modulation in bacterial infections: implications in persistence and clearance

Pathogenic bacteria trigger complex molecular interactions in hosts that are characterized mainly by an increase in reactive oxygen species (ROS) as well as an inflammation-associated response. To counteract oxidative damage, cells respond through protective mechanisms to promote resistance and avoi...

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Bibliographic Details
Main Authors: Marco Antonio Romero-Durán, Octavio Silva-García, Jose Manuel Perez-Aguilar, Víctor Manuel Baizabal-Aguirre
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
KEAP1
Nrf2
bacteria
infection
inflammatory mechanisms
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1508787/full
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