Fluid Retention Caused by Rosiglitazone Is Related to Increases in AQP2 and αENaC Membrane Expression

Fluid Retention Caused by Rosiglitazone Is Related to Increases in AQP2 and αENaC Membrane Expression

Peroxisome proliferator activated receptor-γ (PPARγ) is a ligand-activated transcription factor of the nuclear hormone receptor superfamily. The decreased phosphorylation of PPARγ due to rosiglitazone (ROS) is the main reason for the increased insulin sensitivity caused by this antidiabetic drug. Ho...

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Bibliographic Details
Main Authors: Jinghua Xu, Mingyue Pan, Xiaoli Wang, Lishi Xu, Lanfang Li, Cheng Xu
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2017/8130968
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