CARD16 restores tumorigenesis and restraints apoptosis in glioma cells Via FOXO1/TRAIL axis

CARD16 restores tumorigenesis and restraints apoptosis in glioma cells Via FOXO1/TRAIL axis

Abstract A hallmark of glioma cells, particularly glioblastoma multiforme (GBM) cells, is their resistance to apoptosis. Accumulating evidences has demonstrated that CARD16, a caspase recruitment domain (CARD) only protein, enhances both anti-apoptotic and tumorigenic properties. Nevertheless, there...

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Bibliographic Details
Main Authors: Ruoheng Xuan, Tianyu Hu, Lingshan Cai, Beichuan Zhao, Erqiao Han, Zhibo Xia
Format: Article
Language:English
Published: Nature Publishing Group 2024-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-024-07196-2
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