miR-146a-5p suppresses migration and downregulates vimentin and MMP-9 expression in gastric cancer cells

miR-146a-5p suppresses migration and downregulates vimentin and MMP-9 expression in gastric cancer cells

Abstract Gastric cancer (GC) is a significant global health issue, characterized by poor prognosis due to its metastatic nature. This study investigates the role of microRNA-146a-5p (miR-146a-5p) in regulating migration and invasion of KATO III GC cells by targeting vimentin and matrix metalloprotei...

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Bibliographic Details
Main Authors: Amir Baghbanzadeh, Shima Rahmani, Sahand Eslami, Mahya Ahmadpour Youshanlui, Nadia Shafiee, Atefe Shafiee, Amirreza Khalaji, Behzad Baradaran
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
MiR-146a-5p
Gastric cancer (GC)
Migration
Invasion
Vimentin
MMP-9
Online Access:https://doi.org/10.1007/s12672-025-02929-x
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