Systematic comparison of quantity and quality of RNA recovered with commercial FFPE tissue extraction kits

Systematic comparison of quantity and quality of RNA recovered with commercial FFPE tissue extraction kits

Abstract Background FFPE tissue samples are commonly used in biomedical research and are a valuable source for next-generation sequencing in oncology, however, extracting RNA from these samples can be difficult the quantity and quality achieved can impact the downstream analysis. This study compared...

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Main Authors: Sukoluhle Dube, Sharefa Al-Mannai, Li Liu, Sara Tomei, Satanay Hubrack, Shimaa Sherif, Ayesha Jabeen, Eiman I. Ahmed, Apryl Sanchez, William Mifsud, Davide Bedognetti, Wouter Hendrickx, Christophe M. Raynaud
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
FFPE RNA extraction kit
RNA quality
RNA quantity
Online Access:https://doi.org/10.1186/s12967-024-05890-5
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