Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province
The objective of this research was to investigate serotype diversity pattern of dengue hemorrhagic fever virus by using real-time-polymerase chain reaction (RT-PCR) method. It was an explorative laboratory research in endemic dengue fever area in South Sulawesi Province, Indonesia, that is, Makassar...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/9682784 |
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| author | Muh. Taslim A. A. Arsunan Hasanuddin Ishak Sudirman Nasir Andi Nilawati Usman |
| author_facet | Muh. Taslim A. A. Arsunan Hasanuddin Ishak Sudirman Nasir Andi Nilawati Usman |
| author_sort | Muh. Taslim |
| collection | DOAJ |
| description | The objective of this research was to investigate serotype diversity pattern of dengue hemorrhagic fever virus by using real-time-polymerase chain reaction (RT-PCR) method. It was an explorative laboratory research in endemic dengue fever area in South Sulawesi Province, Indonesia, that is, Makassar municipality and Maros and Gowa region. Serological examination was carried out using real-time-polymerase chain reaction (RT-PCR) method to determine the serotype of dengue virus. The data showed that, of 30 patients, 20 patients (66.67%) were from Makassar municipality: 10 patients (33.33%) from Gowa region and 10 patients (33.33%) from Maros region. The serotypes found were DENV-2 and DENV-4 and no DENV-1 and DENV-3 serotypes were found. Makassar municipality and Gowa region have higher infection with serotype DENV-2, that is, 40% of cases compared with Maros, which is 20.0%. Statistical test results showed no significant differences between the three endemic areas. Maros region has the highest infection with serotype DENV-4, that is, 40% of cases compared with Makassar municipality (5.0%) and Gowa region (0%). Statistical test results showed significant differences between the three endemic areas. This result revealed that serotypes obtained in endemic areas of dengue fever in South Sulawesi are DENV-2 and DENV-4 and not serotypes DENV-1 and DENV-3. Makassar municipality has DENV-2 and DENV-4 serotype, infection dominated by DENV-2, while Maros region also has DENV-2 and DENV-4, but DENV-4 is the dominant serotype. Gowa municipality only has DENV-2 serotype infection. |
| format | Article |
| id | doaj-art-d147ede1665541cab841d02ec397c2cc |
| institution | DOAJ |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-d147ede1665541cab841d02ec397c2cc2025-08-20T03:24:01ZengWileyJournal of Tropical Medicine1687-96861687-96942018-01-01201810.1155/2018/96827849682784Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi ProvinceMuh. Taslim0A. A. Arsunan1Hasanuddin Ishak2Sudirman Nasir3Andi Nilawati Usman4Doctoral Program, Faculty of Medicine, Hasanuddin University, Makassar, IndonesiaDepartment of Epidemiology, Faculty of Public Health, Hasanuddin University, Makassar, IndonesiaDepartment of Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar, IndonesiaDepartment of Health Promotion, Faculty of Public Health, Hasanuddin University, Makassar, IndonesiaDepartment of Public Health, Mandala Waluya College, Kendari, IndonesiaThe objective of this research was to investigate serotype diversity pattern of dengue hemorrhagic fever virus by using real-time-polymerase chain reaction (RT-PCR) method. It was an explorative laboratory research in endemic dengue fever area in South Sulawesi Province, Indonesia, that is, Makassar municipality and Maros and Gowa region. Serological examination was carried out using real-time-polymerase chain reaction (RT-PCR) method to determine the serotype of dengue virus. The data showed that, of 30 patients, 20 patients (66.67%) were from Makassar municipality: 10 patients (33.33%) from Gowa region and 10 patients (33.33%) from Maros region. The serotypes found were DENV-2 and DENV-4 and no DENV-1 and DENV-3 serotypes were found. Makassar municipality and Gowa region have higher infection with serotype DENV-2, that is, 40% of cases compared with Maros, which is 20.0%. Statistical test results showed no significant differences between the three endemic areas. Maros region has the highest infection with serotype DENV-4, that is, 40% of cases compared with Makassar municipality (5.0%) and Gowa region (0%). Statistical test results showed significant differences between the three endemic areas. This result revealed that serotypes obtained in endemic areas of dengue fever in South Sulawesi are DENV-2 and DENV-4 and not serotypes DENV-1 and DENV-3. Makassar municipality has DENV-2 and DENV-4 serotype, infection dominated by DENV-2, while Maros region also has DENV-2 and DENV-4, but DENV-4 is the dominant serotype. Gowa municipality only has DENV-2 serotype infection.http://dx.doi.org/10.1155/2018/9682784 |
| spellingShingle | Muh. Taslim A. A. Arsunan Hasanuddin Ishak Sudirman Nasir Andi Nilawati Usman Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province Journal of Tropical Medicine |
| title | Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province |
| title_full | Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province |
| title_fullStr | Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province |
| title_full_unstemmed | Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province |
| title_short | Diversity of Dengue Virus Serotype in Endemic Region of South Sulawesi Province |
| title_sort | diversity of dengue virus serotype in endemic region of south sulawesi province |
| url | http://dx.doi.org/10.1155/2018/9682784 |
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