ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels

BackgroundThe widespread use of zinc oxide nanoparticles (ZnO NPs) has raised safety concerns on human health. However, the effects and underlying mechanisms of ZnO NPs exposure on the heart, especially during acute exposure, have yet to be elucidated.MethodsTwo different sizes of ZnO NPs (40 nm and...

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Bibliographic Details
Main Authors:	Xuexue Liu, Hongmei Deng, Zijuan Zhao, Shan Wen, Kailong Ma, Xinyu Wang, Yanfei Du, Chang Li, Jun Li, Guangqin Zhang, Xiaobo Zhou, Tuck Wah Soong, Ziqi Yuan, Jian Feng, Guang Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	zinc oxide nanoparticles heart failure cardiac arrhythmia ion channels calcium homeostasis
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1569265/full
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ZnO nanoparticles induce acute arrhythmia and heart failure in mice by disturbing cardiac ion channels

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