Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases

Currently the main way of curable treatment of hepatocellular carcinomas (HCC)* is a liver resection. Candidates for surgery are patient with good score of liver function (Child-Pugh A group), without destruction of great vessels and distant metastases. Hemihepatectomy is associated with a high risk...

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Main Authors: D. V. Sidorov, M. V. Lozhkin, L. O. Petrov, A. G. Isaeva, M. S. Gusakova
Format: Article
Language:Russian
Published: QUASAR, LLC 2020-06-01
Series:Исследования и практика в медицине
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Online Access:https://www.rpmj.ru/rpmj/article/view/548
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author D. V. Sidorov
M. V. Lozhkin
L. O. Petrov
A. G. Isaeva
M. S. Gusakova
author_facet D. V. Sidorov
M. V. Lozhkin
L. O. Petrov
A. G. Isaeva
M. S. Gusakova
author_sort D. V. Sidorov
collection DOAJ
description Currently the main way of curable treatment of hepatocellular carcinomas (HCC)* is a liver resection. Candidates for surgery are patient with good score of liver function (Child-Pugh A group), without destruction of great vessels and distant metastases. Hemihepatectomy is associated with a high risk of postoperative liver failure (including portal hypertension, cirrhosis, portal vein thrombosis). This reason leads to premature failure of the operation. According to current clinical guidelines, system therapy is more suitable, despite of the lack of reliable data on its effectiveness in such clinical situations. The presented cases may support the selection of advanced hemihepatectomy as a treatment for hepatocellular cancer C stage BCLC classification.
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institution Kabale University
issn 2410-1893
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publishDate 2020-06-01
publisher QUASAR, LLC
record_format Article
series Исследования и практика в медицине
spelling doaj-art-d145bd73d5fa4c62ac78ea3dbd6c7dee2025-08-20T04:00:14ZrusQUASAR, LLCИсследования и практика в медицине2410-18932020-06-017215416310.17709/2409-2231-2020-7-2-14329Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical casesD. V. Sidorov0M. V. Lozhkin1L. O. Petrov2A. G. Isaeva3M. S. Gusakova4P.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological CentreP.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological CentreA.F.Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological CenterA.F.Tsyb Medical Radiological Research Center – Branch of the National Medical Research Radiological CenterP.A.Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological CentreCurrently the main way of curable treatment of hepatocellular carcinomas (HCC)* is a liver resection. Candidates for surgery are patient with good score of liver function (Child-Pugh A group), without destruction of great vessels and distant metastases. Hemihepatectomy is associated with a high risk of postoperative liver failure (including portal hypertension, cirrhosis, portal vein thrombosis). This reason leads to premature failure of the operation. According to current clinical guidelines, system therapy is more suitable, despite of the lack of reliable data on its effectiveness in such clinical situations. The presented cases may support the selection of advanced hemihepatectomy as a treatment for hepatocellular cancer C stage BCLC classification.https://www.rpmj.ru/rpmj/article/view/548hemihepatectomyhepatocellular carcinomabclc classificationcirrhosisportal vein thrombosisprognosis
spellingShingle D. V. Sidorov
M. V. Lozhkin
L. O. Petrov
A. G. Isaeva
M. S. Gusakova
Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
Исследования и практика в медицине
hemihepatectomy
hepatocellular carcinoma
bclc classification
cirrhosis
portal vein thrombosis
prognosis
title Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
title_full Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
title_fullStr Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
title_full_unstemmed Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
title_short Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
title_sort combined extensive liver resections in patients with locally advanced hepatocellular cancer clinical cases
topic hemihepatectomy
hepatocellular carcinoma
bclc classification
cirrhosis
portal vein thrombosis
prognosis
url https://www.rpmj.ru/rpmj/article/view/548
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AT lopetrov combinedextensiveliverresectionsinpatientswithlocallyadvancedhepatocellularcancerclinicalcases
AT agisaeva combinedextensiveliverresectionsinpatientswithlocallyadvancedhepatocellularcancerclinicalcases
AT msgusakova combinedextensiveliverresectionsinpatientswithlocallyadvancedhepatocellularcancerclinicalcases