Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer
Highlights 1. Inhibition of circ_0000144 repressed malignant behaviors and angiogenesis of PTC cells in vitro. 2. Knockdown of circ_0000144 constrained PTC cell proliferation in vivo. 3. Circ_0000144 acted as a miR-1178-3p sponge. 4. YWHAH acted as a downstream target for miR-1178-3p.
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| Main Authors: | Yinli Ma, Dan Yang, Pingan Guo |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-07-01
|
| Series: | Journal of Otolaryngology - Head and Neck Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40463-022-00574-w |
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