Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions
Background: Vasoconstrictors with local anesthetics provide a bloodless as well as toxicity-free area for effortless extraction tooth. This study was conducted to evaluate the effect of local anesthesia (LA) with adrenaline and without adrenaline on blood glycemic levels in patients undergoing tooth...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_805_24 |
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| author | Sujata Kumari Chandandeep Singh Riya Jaitly Suresh B. Kondaveeti Mohamed S. M. Morsy Ahtesham A. Qurishi Akshaya Ojha |
| author_facet | Sujata Kumari Chandandeep Singh Riya Jaitly Suresh B. Kondaveeti Mohamed S. M. Morsy Ahtesham A. Qurishi Akshaya Ojha |
| author_sort | Sujata Kumari |
| collection | DOAJ |
| description | Background:
Vasoconstrictors with local anesthetics provide a bloodless as well as toxicity-free area for effortless extraction tooth. This study was conducted to evaluate the effect of local anesthesia (LA) with adrenaline and without adrenaline on blood glycemic levels in patients undergoing tooth extraction.
Material and Method:
A total of 120 patients who require multiple extractions consisting of 60 healthy and 60 diabetic patients in need of multiple extractions were selected for this study. Subjects were given plain lignocaine on their 1st visit and tooth extraction was performed. After seven days lignocaine with 1:80,000 adrenaline was administered to the same patient for a similar procedure. Blood glycemic levels were estimated at regular intervals that is before and right away after the administration of LA) 10 and 20 min on both occasions.
Results:
Comparing the glucose level at 10 min and 20 min showed a statistically significant distinction (P < 0.001) in healthy subjects. Comparing the glucose level at 10 min and 20 min intervals showed highly statistically significant distinction (P < 0.001) in diabetic subjects (P < 0.001).
Conclusion:
LA with vasoconstrictor leads to an elevation in blood glycemic level in patients with NIDDM. |
| format | Article |
| id | doaj-art-d1302786c56e4313bd036d3a017f04fa |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-d1302786c56e4313bd036d3a017f04fa2025-01-12T14:19:43ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062024-12-0116Suppl 4S3329S333110.4103/jpbs.jpbs_805_24Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth ExtractionsSujata KumariChandandeep SinghRiya JaitlySuresh B. KondaveetiMohamed S. M. MorsyAhtesham A. QurishiAkshaya OjhaBackground: Vasoconstrictors with local anesthetics provide a bloodless as well as toxicity-free area for effortless extraction tooth. This study was conducted to evaluate the effect of local anesthesia (LA) with adrenaline and without adrenaline on blood glycemic levels in patients undergoing tooth extraction. Material and Method: A total of 120 patients who require multiple extractions consisting of 60 healthy and 60 diabetic patients in need of multiple extractions were selected for this study. Subjects were given plain lignocaine on their 1st visit and tooth extraction was performed. After seven days lignocaine with 1:80,000 adrenaline was administered to the same patient for a similar procedure. Blood glycemic levels were estimated at regular intervals that is before and right away after the administration of LA) 10 and 20 min on both occasions. Results: Comparing the glucose level at 10 min and 20 min showed a statistically significant distinction (P < 0.001) in healthy subjects. Comparing the glucose level at 10 min and 20 min intervals showed highly statistically significant distinction (P < 0.001) in diabetic subjects (P < 0.001). Conclusion: LA with vasoconstrictor leads to an elevation in blood glycemic level in patients with NIDDM.https://journals.lww.com/10.4103/jpbs.jpbs_805_24adrenalinediabetic patientglycemic levelvasoconstrictor |
| spellingShingle | Sujata Kumari Chandandeep Singh Riya Jaitly Suresh B. Kondaveeti Mohamed S. M. Morsy Ahtesham A. Qurishi Akshaya Ojha Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions Journal of Pharmacy and Bioallied Sciences adrenaline diabetic patient glycemic level vasoconstrictor |
| title | Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions |
| title_full | Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions |
| title_fullStr | Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions |
| title_full_unstemmed | Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions |
| title_short | Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions |
| title_sort | effect of local anesthesia with and without the vasoconstrictor on blood glycemic level in diabetic patients undergoing tooth extractions |
| topic | adrenaline diabetic patient glycemic level vasoconstrictor |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_805_24 |
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